Vasotec and Multihance drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vasotec (enalapril maleate) and Multihance (gadobenate dimeglumine). Common drug interactions include nephrogenic systemic fibrosis among females and nephrogenic systemic fibrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Vasotec and Multihance. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Vasotec?

Vasotec has active ingredients of enalapril maleate. It is often used in high blood pressure. eHealthMe is studying from 14,646 Vasotec users. Check the latest studies of Vasotec.

What is Multihance?

Multihance has active ingredients of gadobenate dimeglumine. eHealthMe is studying from 5,786 Multihance users. Check the latest studies of Multihance.



On Jul, 14, 2026

28 people who take Vasotec and Multihance together, and have interactions are studied.

Vasotec and Multihance drug interactions.

What are the common drug interactions of Vasotec and Multihance, by gender? *:

female:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  2. Pain
  3. Skin tightness
  4. Skin induration (an abnormally hard spot or area on the skin)
  5. Pain in extremity
  6. Erythema (redness of the skin)
  7. Mobility decreased (ability to move is reduced)
  8. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  9. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
  10. Oedema peripheral (superficial swelling)

male:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  2. Pain
  3. Injury
  4. Neuropathy peripheral (surface nerve damage)
  5. Sensory loss (senses loss)
  6. Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
  7. Skin induration (an abnormally hard spot or area on the skin)
  8. Arthralgia (joint pain)
  9. Bone pain
  10. Deformity (disfigurement)

What are the common drug interactions of Vasotec and Multihance, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Mobility decreased (ability to move is reduced)
  2. Muscle tightness
  3. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  4. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  5. Pain
  6. Pruritus generalised (generalized itching)
  7. Rash erythematous (redness of the skin)
  8. Scar
  9. Skin discolouration (change of skin colour)
  10. Skin hypertrophy (skin cells enlarges)

30-39:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  2. Pain
  3. Skin induration (an abnormally hard spot or area on the skin)
  4. Axonal neuropathy (dysfunction of axon nerves)
  5. Deformity (disfigurement)
  6. Erythema (redness of the skin)
  7. Muscle spasms (muscle contraction)
  8. Myositis (inflammation of the muscles)
  9. Rash
  10. Rash papular (redness with papule)

40-49:

  1. Anaphylactic reaction (serious allergic reaction)

50-59:

  1. Injury
  2. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  3. Pain
  4. Anxiety
  5. Emotional distress
  6. Mobility decreased (ability to move is reduced)
  7. Skin tightness
  8. Oedema peripheral (superficial swelling)
  9. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
  10. General physical health deterioration (weak health status)

60+:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  2. Pain
  3. Erythema (redness of the skin)
  4. Arthralgia (joint pain)
  5. Bone pain
  6. Deformity (disfigurement)
  7. Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
  8. Eye disorder
  9. General physical health deterioration (weak health status)
  10. Joint range of motion decreased (disease of joint movement)

What are the existing conditions these people have? *

  1. Diabetes: 5 people, 17.86%
  2. Computerised Tomogram Abdomen: 5 people, 17.86%
  3. Anaemia (lack of blood): 3 people, 10.71%
  4. Nuclear Magnetic Resonance Imaging Brain: 2 people, 7.14%
  5. Cardiac Failure Chronic: 2 people, 7.14%
  6. Blood Pressure Abnormal: 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Vasotec and Multihance?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vasotec and Multihance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vasotec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Multihance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vasotec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Multihance and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on enalapril maleate and gadobenate dimeglumine (the active ingredients of Vasotec and Multihance, respectively), and Vasotec and Multihance (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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