Vasotec and Piperacillin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vasotec (enalapril maleate) and Piperacillin (piperacillin sodium). Common drug interactions include proctalgia among females and hyperkalaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Vasotec and Piperacillin. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Vasotec?

Vasotec has active ingredients of enalapril maleate. It is often used in high blood pressure. eHealthMe is studying from 14,646 Vasotec users. Check the latest studies of Vasotec.

What is Piperacillin?

Piperacillin has active ingredients of piperacillin sodium. eHealthMe is studying from 5,597 Piperacillin users. Check the latest studies of Piperacillin.



On Jul, 11, 2026

11 people who take Vasotec and Piperacillin together, and have interactions are studied.

Vasotec and Piperacillin drug interactions.

What are the common drug interactions of Vasotec and Piperacillin, by gender? *:

female:

  1. Proctalgia (pain in the rectum)
  2. Proteinuria (presence of protein in the urine)
  3. Proteinuria present
  4. Pruritus (severe itching of the skin)
  5. Chest pain
  6. Pneumonia
  7. Renal failure (kidney dysfunction)
  8. Anaemia (lack of blood)
  9. Dyspnoea (difficult or laboured respiration)
  10. Haematocrit decreased

male:

  1. Hyperkalaemia (damage to or disease of the kidney)
  2. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  3. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  4. Ventricular fibrillation (abnormally irregular heart rhythm)
  5. Blood potassium decreased
  6. Cough
  7. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  8. Drug eruption (adverse drug reaction of the skin)
  9. Dyspnoea (difficult or laboured respiration)
  10. Electrolyte imbalance

What are the common drug interactions of Vasotec and Piperacillin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Hyperadrenalism (excessive levels of adrenal hormones in the body)
  2. Hypokalaemia (low potassium)
  3. Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
  4. Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
  5. Intracranial pressure increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid)
  6. Iron deficiency anaemia
  7. Ketonuria (ketones in urine)
  8. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
  9. Nausea (feeling of having an urge to vomit)
  10. Oedema (fluid collection in tissue)

50-59:

  1. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  2. Brain hypoxia (reduced supply of oxygen to the brain)
  3. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  4. Pneumonia
  5. Pruritus (severe itching of the skin)
  6. Renal impairment (severely reduced kidney function)
  7. Stevens johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  8. Systemic sclerosis (an autoimmune or connective tissue disease. it is characterized by thickening of the skin)

60+:

  1. Renal failure (kidney dysfunction)
  2. Anaemia (lack of blood)
  3. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  4. Multi-organ failure (multisystem organ failure)
  5. Myalgia (muscle pain)
  6. Pleural effusion (water on the lungs)
  7. Pneumonia
  8. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  9. Ventricular fibrillation (abnormally irregular heart rhythm)
  10. Alveolitis fibrosing (idiopathic pulmonary fibrosis)

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vasotec and Piperacillin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vasotec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Piperacillin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vasotec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Piperacillin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on enalapril maleate and piperacillin sodium (the active ingredients of Vasotec and Piperacillin, respectively), and Vasotec and Piperacillin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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