Vasotec and Prometrium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vasotec (enalapril maleate) and Prometrium (progesterone). Common drug interactions include abdominal distension among females.

The phase IV clinical study analyzes what interactions people have when they take Vasotec and Prometrium. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Vasotec?

Vasotec has active ingredients of enalapril maleate. It is often used in high blood pressure. eHealthMe is studying from 14,646 Vasotec users. Check the latest studies of Vasotec.

What is Prometrium?

Prometrium has active ingredients of progesterone. It is often used in menopause. eHealthMe is studying from 5,980 Prometrium users. Check the latest studies of Prometrium.



On Jul, 17, 2026

12 people who take Vasotec and Prometrium together, and have interactions are studied.

Vasotec and Prometrium drug interactions.

What are the common drug interactions of Vasotec and Prometrium, by gender? *:

female:

  1. Abdominal distension
  2. Breast cancer female
  3. Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
  4. Burning sensation
  5. Cataract (clouding of the lens inside the eye)
  6. Constipation
  7. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  8. Cough
  9. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  10. Drug ineffective

male:

n/a

What are the common drug interactions of Vasotec and Prometrium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
  2. Constipation
  3. Drug ineffective
  4. Fatigue (feeling of tiredness)
  5. Flatulence (flatus expelled through the anus)
  6. Haemorrhoids (a swollen vein or group of veins in the region of the anus)
  7. Hyperglycaemia (high blood sugar)
  8. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  9. Steatorrhoea (presence of excess fat in faeces)
  10. Weight decreased

50-59:

  1. Cough
  2. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  3. Hyperaesthesia
  4. Palpitations (feelings or sensations that your heart is pounding or racing)
  5. Urticaria (rash of round, red welts on the skin that itch intensely)

60+:

  1. Breast cancer female
  2. Alopecia (absence of hair from areas of the body)
  3. Glossitis (infection of tongue with soreness)
  4. Joint injury
  5. Joint swelling
  6. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  7. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  8. Pruritus (severe itching of the skin)
  9. Sensation of foreign body
  10. Tongue oedema (swelling of tongue)

What are the existing conditions these people have? *

  1. Thyroid Diseases: 2 people, 16.67%
  2. Quit Smoking: 2 people, 16.67%
  3. Arrhythmias (irregular heartbeat): 2 people, 16.67%
  4. Stomach Discomfort (pain in abdomen): 1 person, 8.33%
  5. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 8.33%
  6. Osteoporosis (bones weak and more likely to break): 1 person, 8.33%
  7. Insomnia (sleeplessness): 1 person, 8.33%
  8. Indigestion: 1 person, 8.33%
  9. High Blood Cholesterol: 1 person, 8.33%
  10. Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Vasotec and Prometrium?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vasotec and Prometrium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vasotec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Prometrium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vasotec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prometrium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on enalapril maleate and progesterone (the active ingredients of Vasotec and Prometrium, respectively), and Vasotec and Prometrium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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