Vasotec and Sulindac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vasotec (enalapril maleate) and Sulindac (sulindac). Common drug interactions include cardiac failure congestive among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Vasotec and Sulindac. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Vasotec?

Vasotec has active ingredients of enalapril maleate. It is often used in high blood pressure. eHealthMe is studying from 14,646 Vasotec users. Check the latest studies of Vasotec.

What is Sulindac?

Sulindac has active ingredients of sulindac. It is often used in rheumatoid arthritis. eHealthMe is studying from 3,824 Sulindac users. Check the latest studies of Sulindac.



On Aug, 10, 2026

12 people who take Vasotec and Sulindac together, and have interactions are studied.

Vasotec and Sulindac drug interactions.

What are the common drug interactions of Vasotec and Sulindac, by gender? *:

female:

  1. Cardiac failure congestive
  2. Cellulitis (infection under the skin)
  3. Sepsis (a severe blood infection that can lead to organ failure and death)
  4. Abdominal distension
  5. Anaemia (lack of blood)
  6. Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
  7. Arrhythmia (irregular heartbeat)
  8. Aspartate aminotransferase increased
  9. Blood albumin decreased
  10. Blood bilirubin increased

male:

  1. Cardiac failure congestive
  2. Muscle weakness (a lack of muscle strength)
  3. Hepatic function abnormal
  4. Hypoaesthesia (reduced sense of touch or sensation)
  5. Mucosal inflammation (infection of mucous membrane)
  6. Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
  7. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  8. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  9. Pyrexia (fever)
  10. Rigors (an episode of shaking or exaggerated shivering)

What are the common drug interactions of Vasotec and Sulindac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Dehydration (dryness resulting from the removal of water)
  2. Diarrhoea
  3. Hepatic function abnormal
  4. Hypoaesthesia (reduced sense of touch or sensation)
  5. Mucosal inflammation (infection of mucous membrane)
  6. Muscle weakness (a lack of muscle strength)
  7. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  8. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  9. Pyrexia (fever)
  10. Rigors (an episode of shaking or exaggerated shivering)

50-59:

  1. Cellulitis (infection under the skin)
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Cardiac failure congestive
  4. Infection
  5. Pulmonary oedema (fluid accumulation in the lungs)

60+:

  1. Cardiac failure congestive
  2. Abdominal distension
  3. Cardiomegaly (increased size of heart than normal)
  4. Chemical injury
  5. Confusion
  6. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  7. Duodenal ulcer
  8. Dyspnoea exertional (breathlessness or shortness of breath)
  9. Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
  10. Erythema (redness of the skin)

What are the existing conditions these people have? *

  1. Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Vasotec and Sulindac?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vasotec and Sulindac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vasotec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sulindac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vasotec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sulindac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on enalapril maleate and sulindac (the active ingredients of Vasotec and Sulindac, respectively), and Vasotec and Sulindac (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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