Velcade and Vimovo drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Velcade (bortezomib) and Vimovo (esomeprazole magnesium; naproxen). Common drug interactions include clostridium difficile colitis among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Velcade and Vimovo. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Velcade?

Velcade has active ingredients of bortezomib. It is often used in multiple myeloma. eHealthMe is studying from 66,422 Velcade users. Check the latest studies of Velcade.

What is Vimovo?

Vimovo has active ingredients of esomeprazole magnesium; naproxen. It is often used in osteoarthritis. eHealthMe is studying from 9,608 Vimovo users. Check the latest studies of Vimovo.

On Jul, 06, 2026

13 people who take Velcade and Vimovo together, and have interactions are studied.

What are the common drug interactions of Velcade and Vimovo, by gender? *:

female:

Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Abdominal compartment syndrome (increased pressure in abdomen)
Anaemia (lack of blood)
Cholecystitis (infection of gallbladder)
Depression
Drug effect decreased
Drug ineffective
Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
Limb discomfort (discomfort in leg)

male:

Dyspnoea (difficult or laboured respiration)
Neuropathy peripheral (surface nerve damage)
Fatigue (feeling of tiredness)
Haemoglobin decreased
Injection site bruising
Lip dry
Lower respiratory tract infection
Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
Decreased appetite
Depression

What are the common drug interactions of Velcade and Vimovo, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Decreased appetite
Depression
Weight decreased
Lung adenocarcinoma (a form of non-small cell lung cancer)
Chronic kidney disease
Renal failure (kidney dysfunction)

60+:

Neuropathy peripheral (surface nerve damage)
Anaemia (lack of blood)
Fatigue (feeling of tiredness)
Haemoglobin decreased
Injection site bruising
Lip dry
Lower respiratory tract infection
Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Abdominal compartment syndrome (increased pressure in abdomen)

What are the existing conditions these people have? *

Pain: 4 people, 30.77%
Respiratory Tract Infection: 3 people, 23.08%
Joint Pain: 3 people, 23.08%
Sleep Disorder: 2 people, 15.38%
Multiple Allergies (allergy to multiple agents): 2 people, 15.38%
High Blood Cholesterol: 1 person, 7.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 7.69%
Blood Pressure Abnormal: 1 person, 7.69%
Anaemia (lack of blood): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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