Veletri and Zaroxolyn drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Veletri (epoprostenol sodium) and Zaroxolyn (metolazone). Common drug interactions include fluid overload among females and pulmonary hypertension among males.

The phase IV clinical study analyzes what interactions people have when they take Veletri and Zaroxolyn. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Veletri?

Veletri has active ingredients of epoprostenol sodium. eHealthMe is studying from 14,196 Veletri users. Check the latest studies of Veletri.

What is Zaroxolyn?

Zaroxolyn has active ingredients of metolazone. It is often used in high blood pressure. eHealthMe is studying from 5,244 Zaroxolyn users. Check the latest studies of Zaroxolyn.

On Jul, 16, 2026

34 people who take Veletri and Zaroxolyn together, and have interactions are studied.

Veletri and Zaroxolyn drug interactions.

What are the common drug interactions of Veletri and Zaroxolyn, by gender? *:

female:

Fluid overload (too much fluid in the blood)
Limb injury
Oedema peripheral (superficial swelling)
Pain
Peripheral swelling
Wound
Acute respiratory distress syndrome
Blood creatinine increased
Cardiac arrest
Hepatic ischaemia (liver does not get enough blood or oxygen, causing injury to liver cells)

male:

Pulmonary hypertension (increase in blood pressure in the lung artery)
Asthenia (weakness)
Pain
Pain in jaw
Renal failure (kidney dysfunction)
Somnolence (a state of near-sleep, a strong desire for sleep)
Tremor (trembling or shaking movements in one or more parts of your body)
Pruritus (severe itching of the skin)
Right ventricular failure (right half of the heart fails to work)
Anxiety

What are the common drug interactions of Veletri and Zaroxolyn, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Chronic respiratory failure
Dyspnoea (difficult or laboured respiration)
Fluid overload (too much fluid in the blood)
Lung transplant
Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
Respiratory syncytial virus infection (viral disease of respiratory system)
Syncope (loss of consciousness with an inability to maintain postural tone)

30-39:

Cellulitis (infection under the skin)
Erythema (redness of the skin)
Oedema (fluid collection in tissue)
Paracentesis
Peripheral swelling
Renal failure (kidney dysfunction)

40-49:

Dyspnoea (difficult or laboured respiration)
Asthenia (weakness)
Blood potassium decreased
Dyspnoea exertional (breathlessness or shortness of breath)
Fluid retention (an abnormal accumulation of fluid in the blood)
Acute respiratory distress syndrome
Blood creatinine increased
Cellulitis (infection under the skin)
Diarrhoea
Hepatic ischaemia (liver does not get enough blood or oxygen, causing injury to liver cells)

50-59:

Heart rate increased
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Palpitations (feelings or sensations that your heart is pounding or racing)
Platelet count decreased
Pulmonary oedema (fluid accumulation in the lungs)
Upper respiratory tract infection
Arrhythmia (irregular heartbeat)
Death
Contusion (a type of hematoma of tissue in which capillaries)
Fall

60+:

Dyspnoea (difficult or laboured respiration)
Nausea (feeling of having an urge to vomit)
Chest pain
Headache (pain in head)
Renal failure (kidney dysfunction)
Somnolence (a state of near-sleep, a strong desire for sleep)
Tremor (trembling or shaking movements in one or more parts of your body)
Oedema (fluid collection in tissue)
Pruritus (severe itching of the skin)
Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 21 people, 61.76%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 15 people, 44.12%
Migraine (headache): 4 people, 11.76%
Diarrhea: 4 people, 11.76%
Stress And Anxiety: 3 people, 8.82%
Nausea And Vomiting: 3 people, 8.82%
Nausea (feeling of having an urge to vomit): 3 people, 8.82%
Upper-Airway Cough Syndrome: 2 people, 5.88%
Oedema Peripheral (superficial swelling): 2 people, 5.88%
Oedema (fluid collection in tissue): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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