Verapamil hcl and Lanoxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Verapamil hcl (verapamil hydrochloride) and Lanoxin (digoxin). Common drug interactions include asthenia among females and gastrointestinal haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Verapamil hcl and Lanoxin. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Verapamil hcl?

Verapamil hcl has active ingredients of verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 5,807 Verapamil hcl users. Check the latest studies of Verapamil hcl.

What is Lanoxin?

Lanoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 21,852 Lanoxin users. Check the latest studies of Lanoxin.



On Jul, 09, 2026

34 people who take Verapamil hcl and Lanoxin together, and have interactions are studied.

Verapamil hcl and Lanoxin drug interactions.

What are the common drug interactions of Verapamil Hcl and Lanoxin, by gender? *:

female:

  1. Asthenia (weakness)
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Decreased appetite
  4. Depressed mood
  5. Dysstasia (difficulty in standing)
  6. Gait disturbance
  7. Memory impairment
  8. Nausea (feeling of having an urge to vomit)
  9. Urinary incontinence (inability to control the flow of urine and involuntary urination)
  10. Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)

male:

  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  2. Anticoagulation drug level above therapeutic
  3. Muscular weakness (muscle weakness)
  4. Oedema (fluid collection in tissue)
  5. Pulmonary embolism (blockage of the main artery of the lung)
  6. Rectal haemorrhage (bleeding from anus)
  7. Vomiting
  8. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  9. Drug level decreased
  10. Drug maladministration

What are the common drug interactions of Verapamil Hcl and Lanoxin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  2. Drug maladministration
  3. Hypertensive heart disease
  4. Oesophageal erosions (wear and tear of oesophagus mucous membrane and tissue)
  5. Pleural effusion (water on the lungs)
  6. Ventricular hypertrophy (enlargement of ventricles (lower chambers) in the heart)

60+:

  1. Malaise (a feeling of general discomfort or uneasiness)
  2. Asthenia (weakness)
  3. Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
  4. Cough
  5. Dyspnoea (difficult or laboured respiration)
  6. Fatigue (feeling of tiredness)
  7. Oedema (fluid collection in tissue)
  8. Vomiting
  9. Anticoagulation drug level above therapeutic
  10. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

What are the existing conditions these people have? *

  1. Neuropathy Peripheral (surface nerve damage): 5 people, 14.71%
  2. Hypoaesthesia (reduced sense of touch or sensation): 5 people, 14.71%
  3. Diabetes: 5 people, 14.71%
  4. Urinary Incontinence (inability to control the flow of urine and involuntary urination): 4 people, 11.76%
  5. Parkinson's Disease: 4 people, 11.76%
  6. Indigestion: 4 people, 11.76%
  7. Diabetic Complication: 4 people, 11.76%
  8. Chest Pain: 4 people, 11.76%
  9. Back Disorder: 4 people, 11.76%
  10. Migraine (headache): 3 people, 8.82%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Verapamil hcl and Lanoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Verapamil hcl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lanoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Verapamil hcl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lanoxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on verapamil hydrochloride and digoxin (the active ingredients of Verapamil hcl and Lanoxin, respectively), and Verapamil hcl and Lanoxin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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