Versed and Sulfatrim drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Versed (midazolam hydrochloride) and Sulfatrim (sulfamethoxazole; trimethoprim). Common drug interactions include radiculopathy among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Versed and Sulfatrim. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Versed?

Versed has active ingredients of midazolam hydrochloride. It is often used in sedation during medical procedure. eHealthMe is studying from 6,869 Versed users. Check the latest studies of Versed.

What is Sulfatrim?

Sulfatrim has active ingredients of sulfamethoxazole; trimethoprim. eHealthMe is studying from 4,140 Sulfatrim users. Check the latest studies of Sulfatrim.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 27, 2026

25 people who take Versed and Sulfatrim together, and have interactions are studied.

Versed and Sulfatrim drug interactions.

What are the common drug interactions of Versed and Sulfatrim, by gender? *:

female:

  1. Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
  2. Abdominal pain
  3. Anaemia (lack of blood)
  4. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  5. Colitis (inflammation of colon)
  6. Colitis ulcerative (inflammation of colon with ulcer)
  7. Constipation
  8. Drug ineffective
  9. Dyspepsia (indigestion)
  10. Erythema (redness of the skin)

male:

  1. Anxiety
  2. Emotional distress
  3. Quality of life decreased
  4. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  5. Fear
  6. Pain
  7. Stress
  8. Blindness
  9. Colitis ulcerative (inflammation of colon with ulcer)
  10. Depression

What are the common drug interactions of Versed and Sulfatrim, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Anxiety
  2. Emotional distress
  3. Fear
  4. Pain
  5. Stress
  6. Blindness
  7. Colitis ulcerative (inflammation of colon with ulcer)
  8. Depression
  9. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  10. Memory impairment

50-59:

n/a

60+:

  1. Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
  2. Abdominal pain
  3. Female genital tract fistula (passage in genital tract of female)
  4. Frequent bowel movements
  5. Haematochezia (passage of stools containing blood)
  6. Headache (pain in head)
  7. Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
  8. Nausea (feeling of having an urge to vomit)
  9. Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
  10. Pyrexia (fever)

What are the existing conditions these people have? *

  1. Allergies: 16 people, 64.00%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 16 people, 64.00%
  3. Colitis (inflammation of colon): 12 people, 48.00%
  4. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 10 people, 40.00%
  5. Fever: 9 people, 36.00%
  6. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 8 people, 32.00%
  7. High Blood Pressure: 5 people, 20.00%
  8. Anaemia (lack of blood): 5 people, 20.00%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 20.00%
  10. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 5 people, 20.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Versed and Sulfatrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Versed:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sulfatrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Versed and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sulfatrim and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on midazolam hydrochloride and sulfamethoxazole; trimethoprim (the active ingredients of Versed and Sulfatrim, respectively), and Versed and Sulfatrim (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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