Vfend and Fentanyl citrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vfend (voriconazole) and Fentanyl citrate (fentanyl citrate). Common drug interactions include mallory-weiss syndrome among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Vfend and Fentanyl citrate. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Vfend?

Vfend has active ingredients of voriconazole. It is often used in aspergillosis. eHealthMe is studying from 12,128 Vfend users. Check the latest studies of Vfend.

What is Fentanyl citrate?

Fentanyl citrate has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 21,294 Fentanyl citrate users. Check the latest studies of Fentanyl citrate.

On Aug, 09, 2026

21 people who take Vfend and Fentanyl citrate together, and have interactions are studied.

Vfend and Fentanyl citrate drug interactions.

What are the common drug interactions of Vfend and Fentanyl Citrate, by gender? *:

female:

Mallory-weiss syndrome (gastro-oesophageal laceration syndrome refers to bleeding from tears)
Migraine (headache)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Neck pain
Neoplasm malignant (cancer tumour)
Ocular icterus (presence of jaundice seen in the sclera of the eye)
Osteonecrosis (death of bone)
Pain in extremity
Pyelonephritis (inflammation of kidney caused by bacteria)
Reticulocyte count decreased

male:

Pneumonia
Blindness
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Alanine aminotransferase increased
Anaemia (lack of blood)
Febrile neutropenia (fever with reduced white blood cells)
Haemoglobinuria (the presence of free haemoglobin in the urine)
Headache (pain in head)
Mitral valve incompetence (inefficient heart valve)
Neutropenia (an abnormally low number of neutrophils)

What are the common drug interactions of Vfend and Fentanyl Citrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Hypoproteinaemia (too little prolactin circulating in the blood)
Pneumonia

20-29:

Hepatitis (inflammation of the liver)
Pleural effusion (water on the lungs)
Septic shock (shock due to blood infection)

30-39:

Pneumonia
Abnormal faeces (abnormal stool)
Blood urea increased
Cardiac tamponade (fluid accumulates in heart covering)
Coagulopathy (blood's ability to clot is impaired)
Faeces discoloured
Fasciitis (infection of muscle surrounding tissue)
Hyperglycaemia (high blood sugar)
Neoplasm progression (growth of tumour)
Pericarditis (inflammation of the pericardium)

40-49:

Alanine aminotransferase increased
Gamma-glutamyltransferase increased
Lymphopenia (an abnormally low level of lymphocytes in the blood)
Pneumonia

50-59:

Blindness
Bradycardia (abnormally slow heart action)
Cardiac arrest
Intravascular haemolysis (intravascular rupture of red blood cells with the release of haemoglobin and the cellular constituents into the plasma, or liquid portion of whole blood)
Renal failure acute (rapid kidney dysfunction)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Haemoglobinuria (the presence of free haemoglobin in the urine)
Mitral valve incompetence (inefficient heart valve)
Stress ulcer (single or multiple mucosal defects which can become complicated by upper gastrointestinal bleeding during the physiologic stress of serious illness)

60+:

Hypokalaemia (low potassium)
Herpes zoster
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Erythema (redness of the skin)
Hallucination (an experience involving the perception of something not present)
Neutropenia (an abnormally low number of neutrophils)
Pyrexia (fever)
Rash
Thrombocytopenia (decrease of platelets in blood)
Interstitial lung disease

What are the existing conditions these people have? *

Pneumonia: 7 people, 33.33%
Febrile Neutropenia (fever with reduced white blood cells): 5 people, 23.81%
Thrombocytopenia (decrease of platelets in blood): 3 people, 14.29%
Stomatitis (inflammation of mucous membrane of mouth): 3 people, 14.29%
Adult T-Cell Lymphoma/leukaemia (cancer of the immune system's own t-cells): 3 people, 14.29%
Asthma: 3 people, 14.29%
Constipation: 3 people, 14.29%
Diabetes: 3 people, 14.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 14.29%
Headache (pain in head): 3 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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