Vfend and Lidoderm drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vfend (voriconazole) and Lidoderm (lidocaine). Common drug interactions include pain in jaw among females and hypoxia among males.

The phase IV clinical study analyzes what interactions people have when they take Vfend and Lidoderm. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Vfend?

Vfend has active ingredients of voriconazole. It is often used in aspergillosis. eHealthMe is studying from 12,128 Vfend users. Check the latest studies of Vfend.

What is Lidoderm?

Lidoderm has active ingredients of lidocaine. It is often used in pain. eHealthMe is studying from 10,524 Lidoderm users. Check the latest studies of Lidoderm.

On Jul, 13, 2026

33 people who take Vfend and Lidoderm together, and have interactions are studied.

What are the common drug interactions of Vfend and Lidoderm, by gender? *:

female:

Pain in jaw
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)
Urinary tract infection
Abasia (inability to walk)
Hip fracture
Synovial cyst (cyst of joint filled with synovial fluid)
Depression
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Bedridden
Breast abscess

male:

Hypoxia (low oxygen in tissues)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hypersensitivity
Macule (a discoloured spot on the skin)
Neutropenia (an abnormally low number of neutrophils)
Photosensitivity reaction
Rash
Renal failure chronic (long lasting kidney dysfunction)
Skin lesion

What are the common drug interactions of Vfend and Lidoderm, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)
Blood creatinine increased
Blood lactic acid increased
Blood urea increased
Bone marrow failure
Bradycardia (abnormally slow heart action)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Cytokine storm (over-protective immune response that can actually be fatal)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haematuria (presence of blood in urine)

20-29:

Ankylosing spondylitis (type of arthritis affecting the spine)
Somnolence (a state of near-sleep, a strong desire for sleep)

30-39:

n/a

40-49:

Alcohol abuse
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Lung abscess (pus in lungs)
Dyspnoea (difficult or laboured respiration)
Flushing (the warm, red condition of human skin)
Hypersensitivity
Skin burning sensation

50-59:

Synovial cyst (cyst of joint filled with synovial fluid)
Urinary tract infection
Weight decreased
White blood cell count decreased
Dry mouth
Purulence (containing pus)
Swelling face
Osteonecrosis (death of bone)
Staphylococcal infection (an infection with staphylococcus bacteria)
Hysterectomy

60+:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Anxiety
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Bone marrow failure
Compression fracture (fracture due to pressure caused by injury)
Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
Disability
Fracture
Hydrocephalus (water on the brain)

What are the existing conditions these people have? *

Neoplasm Malignant (cancer tumour): 10 people, 30.30%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 5 people, 15.15%
Nausea (feeling of having an urge to vomit): 5 people, 15.15%
Constipation: 4 people, 12.12%
Fungal Infection: 3 people, 9.09%
Febrile Neutropenia (fever with reduced white blood cells): 3 people, 9.09%
Fever: 2 people, 6.06%
Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 6.06%
Cellulitis (infection under the skin): 2 people, 6.06%
Dry Mouth: 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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