Vfend and Theophylline drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Vfend (voriconazole) and Theophylline (theophylline). Common drug interactions include photophobia among females and alopecia among males.
The phase IV clinical study analyzes what interactions people have when they take Vfend and Theophylline. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.
What is Vfend?
Vfend has active ingredients of voriconazole. It is often used in aspergillosis. eHealthMe is studying from 12,128 Vfend users. Check the latest studies of Vfend.
What is Theophylline?
Theophylline has active ingredients of theophylline. It is often used in asthma. eHealthMe is studying from 19,150 Theophylline users. Check the latest studies of Theophylline.
23 people who take Vfend and Theophylline together, and have interactions are studied.

What are the common drug interactions of Vfend and Theophylline, by gender? *:
female:
- Photophobia (extreme sensitivity to light)
- Abdominal distension
- Abdominal pain
- Ascites (accumulation of fluid in the abdominal cavity)
- Blood bilirubin increased
- Dehydration (dryness resulting from the removal of water)
- Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Infection
- Small intestinal obstruction (blockage in small intestine)
male:
- Alopecia (absence of hair from areas of the body)
- Blood pressure increased
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
- Photophobia (extreme sensitivity to light)
- Swelling
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
- Dizziness
- Fall
- Liver disorder (liver diseases)
- Nausea (feeling of having an urge to vomit)
What are the common drug interactions of Vfend and Theophylline, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Bronchial obstruction (blockage of the breathing passages to the lungs)
- Drug ineffective
- Dysaesthesia (abnormal sensation)
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
- Hypersensitivity
- Burning sensation
- Dyspnoea (difficult or laboured respiration)
- Infection
- Mucous membrane disorder (disease of mucous membrane)
40-49:
- Abasia (inability to walk)
- Alopecia (absence of hair from areas of the body)
- Blood pressure increased
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)
- Cough
- Dyspepsia (indigestion)
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
- Labile blood pressure (wildly fluctuating blood pressure)
- Neuropathy peripheral (surface nerve damage)
50-59:
- Dyspnoea (difficult or laboured respiration)
- Hypercapnia (too much smoke)
60+:
- Hallucination (an experience involving the perception of something not present)
- Malaise (a feeling of general discomfort or uneasiness)
- Multi-organ failure (multisystem organ failure)
- Photophobia (extreme sensitivity to light)
- Aphagia (inability or refusal to swallow)
- Asthenia (weakness)
- Blood pressure decreased
- Chromatopsia (visual defect in which colourless objects appear to be tinged with colour)
- Circulatory collapse
- Dehydration (dryness resulting from the removal of water)
What are the existing conditions these people have? *
- Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 10 people, 43.48%
- Pulmonary Aspergilloma (Mycetoma) (mass caused by a fungal infection that usually grows in lung): 3 people, 13.04%
- Dyspnea (difficult or laboured breathing): 3 people, 13.04%
- Neuropathy Peripheral (surface nerve damage): 2 people, 8.70%
* Approximation only. Some reports may have incomplete information.
Do you take Vfend and Theophylline?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Vfend (12,128 reports)
- Theophylline (19,150 reports)
Browse all drug interactions of Vfend and Theophylline:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Vfend:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Theophylline:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vfend and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Theophylline and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Korang-Yeboah M, Rahman Z, Shah D, Mohammad A, Wu S, Siddiqui A, Khan MA, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International journal of pharmaceutics, 2016 Feb .
- Dhaval MK, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International Journal of Pharmaceutics, 2016 Jan .
- Korang-Yeboah M, Rahman Z, Shah D, Mohammad A, Wu S, Siddiqui A, Khan MA, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International journal of pharmaceutics, 2016 Feb .
- Dhaval MK, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International Journal of Pharmaceutics, 2016 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on voriconazole and theophylline (the active ingredients of Vfend and Theophylline, respectively), and Vfend and Theophylline (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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