Cafergot and Viagra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cafergot (caffeine; ergotamine tartrate) and Viagra (sildenafil citrate). Common drug interactions include depression among males.

The phase IV clinical study analyzes what interactions people have when they take Cafergot and Viagra. It is created by eHealthMe based on reports of 10 people who take the same drugs from the FDA, and is updated regularly.

What is Cafergot?

Cafergot has active ingredients of caffeine; ergotamine tartrate. It is often used in migraine. eHealthMe is studying from 531 Cafergot users. Check the latest studies of Cafergot.

What is Viagra?

Viagra has active ingredients of sildenafil citrate. It is often used in erection problems. eHealthMe is studying from 63,865 Viagra users. Check the latest studies of Viagra.



On Apr, 30, 2026

10 people who take Cafergot and Viagra together, and have interactions are studied.

Cafergot and Viagra drug interactions.

What are the common drug interactions of Cafergot and Viagra, by gender? *:

female:

n/a

male:

  1. Depression
  2. Emotional distress
  3. Drug effect decreased
  4. Drug effect delayed
  5. Drug ineffective
  6. Drug maladministration
  7. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  8. Influenza like illness
  9. Scar
  10. Sinusitis (inflammation of sinus)

What are the common drug interactions of Cafergot and Viagra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Blindness transient (sudden loss of vision)

30-39:

n/a

40-49:

  1. Drug ineffective
  2. Drug maladministration
  3. Headache (pain in head)
  4. Influenza like illness

50-59:

  1. Headache (pain in head)
  2. Sinusitis (inflammation of sinus)

60+:

  1. Drug effect delayed

What are the existing conditions these people have? *

  1. Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 40.00%
  2. Plantar Fasciitis (painful inflammatory process of the plantar fascia): 4 people, 40.00%
  3. Joint Pain: 4 people, 40.00%
  4. High Blood Pressure: 4 people, 40.00%
  5. High Blood Cholesterol: 4 people, 40.00%
  6. Headache (pain in head): 4 people, 40.00%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 40.00%
  8. Diabetes: 4 people, 40.00%
  9. Depression: 4 people, 40.00%
  10. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 10.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cafergot and Viagra:

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Browse all side effects of Viagra:

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Browse all interactions between Cafergot and drugs from A to Z:

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Browse all interactions between Viagra and drugs from A to Z:

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Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on caffeine; ergotamine tartrate and sildenafil citrate (the active ingredients of Cafergot and Viagra, respectively), and Cafergot and Viagra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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