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Viagra and Febuxostat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Viagra (sildenafil citrate) and Febuxostat (febuxostat). Common drug interactions include left ventricular dysfunction among males.

The phase IV clinical study analyzes what interactions people have when they take Viagra and Febuxostat. It is created by eHealthMe based on reports of 9 people who take the same drugs from the FDA, and is updated regularly.

What is Viagra?

Viagra has active ingredients of sildenafil citrate. It is often used in erection problems. eHealthMe is studying from 63,865 Viagra users. Check the latest studies of Viagra.

What is Febuxostat?

Febuxostat has active ingredients of febuxostat. eHealthMe is studying from 9,693 Febuxostat users. Check the latest studies of Febuxostat.

On Jun, 17, 2026

9 people who take Viagra and Febuxostat together, and have interactions are studied.

Viagra and Febuxostat drug interactions.

What are the common drug interactions of Viagra and Febuxostat, by gender? *:

female:

n/a

male:

  1. Left ventricular dysfunction
  2. Angina pectoris (chest pain due to ischemia of the heart muscle)
  3. Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
  4. Myositis (inflammation of the muscles)
  5. Renal failure (kidney dysfunction)
  6. Arthralgia (joint pain)
  7. Blood creatine phosphokinase increased
  8. Blood glucose decreased
  9. Chronic kidney disease
  10. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

What are the common drug interactions of Viagra and Febuxostat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Fatigue (feeling of tiredness)
  2. Myositis (inflammation of the muscles)
  3. Arthralgia (joint pain)
  4. Blood creatine phosphokinase increased

50-59:

  1. Drug ineffective

60+:

  1. Left ventricular dysfunction
  2. Angina pectoris (chest pain due to ischemia of the heart muscle)
  3. Chronic kidney disease
  4. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  5. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  6. Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
  7. Renal failure (kidney dysfunction)

* Approximation only. Some reports may have incomplete information.

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Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Viagra and Febuxostat:

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Browse all side effects of Viagra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Febuxostat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Viagra and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Febuxostat and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on sildenafil citrate and febuxostat (the active ingredients of Viagra and Febuxostat, respectively), and Viagra and Febuxostat (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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