Viagra and Hydroxyurea drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Viagra (sildenafil citrate) and Hydroxyurea (hydroxyurea). Common drug interactions include jugular vein thrombosis among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Viagra and Hydroxyurea. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Viagra?

Viagra has active ingredients of sildenafil citrate. It is often used in erection problems. eHealthMe is studying from 63,865 Viagra users. Check the latest studies of Viagra.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.

On Apr, 29, 2026

36 people who take Viagra and Hydroxyurea together, and have interactions are studied.

Viagra and Hydroxyurea drug interactions.

What are the common drug interactions of Viagra and Hydroxyurea, by gender? *:

female:

Jugular vein thrombosis (clot in jugular vein)
Nervousness
Pain
Pulmonary hypertension (increase in blood pressure in the lung artery)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Balance disorder
Cerebral artery thrombosis (clot formation in brain blood vessels)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest pain

male:

Drug ineffective
Asthenia (weakness)
Ageusia (loss of taste functions of the tongue)
Anaemia (lack of blood)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anosmia (partial or complete loss of the sense of smell)
Anxiety
Atrioventricular block first degree (heart block first degree)
Bone pain
Bradycardia (abnormally slow heart action)

What are the common drug interactions of Viagra and Hydroxyurea, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Cerebral artery thrombosis (clot formation in brain blood vessels)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Dyspnoea (difficult or laboured respiration)
Emotional distress
Fear of disease
General physical health deterioration (weak health status)

20-29:

n/a

30-39:

Drug ineffective
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Rash
Red blood cell count decreased
Tremor (trembling or shaking movements in one or more parts of your body)

40-49:

Weakness
Blood pressure increased
Coordination abnormal (abnormal movement)
Facial palsy (paralysis of face nerve)

50-59:

Fatigue (feeling of tiredness)
Blood iron decreased
Insomnia (sleeplessness)
Drug ineffective
Ageusia (loss of taste functions of the tongue)
Anaemia (lack of blood)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anosmia (partial or complete loss of the sense of smell)
Anxiety
Asthenia (weakness)

60+:

Drug ineffective
Headache (pain in head)
Dehydration (dryness resulting from the removal of water)
Hypotension (abnormally low blood pressure)
Cardiac failure congestive
Chronic myeloid leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood)
Confusional state
Contusion (a type of hematoma of tissue in which capillaries)
Diarrhoea
Disease progression

What are the existing conditions these people have? *

Primary Myelofibrosis (primary disorder of the bone marrow): 12 people, 33.33%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 4 people, 11.11%
Pain: 4 people, 11.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 11.11%
High Blood Pressure: 4 people, 11.11%
Leukaemia (blood or bone marrow cancer): 3 people, 8.33%
Cough: 3 people, 8.33%
Gout (uric acid crystals building up in the body): 3 people, 8.33%
Libido Disorder (a sexual dysfunction relating to loss of sexual desire): 3 people, 8.33%
Irritable Bowel Syndrome: 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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