Lamotrigine and Viagra drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lamotrigine (lamotrigine) and Viagra (sildenafil citrate). Common drug interactions include atrial fibrillation among females and anxiety among males.
The phase IV clinical study analyzes what interactions people have when they take Lamotrigine and Viagra. It is created by eHealthMe based on reports of 93 people who take the same drugs from the FDA, and is updated regularly.
What is Lamotrigine?
Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 76,638 Lamotrigine users. Check the latest studies of Lamotrigine.
What is Viagra?
Viagra has active ingredients of sildenafil citrate. It is often used in erection problems. eHealthMe is studying from 63,865 Viagra users. Check the latest studies of Viagra.
93 people who take Lamotrigine and Viagra together, and have interactions are studied.

What are the common drug interactions of Lamotrigine and Viagra, by gender? *:
female:
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Blood cholesterol increased
- Cardiac pacemaker replacement
- Weight increased
- Drug ineffective
- Nasopharyngitis (inflammation of the nasopharynx)
- Pain in extremity
- Thirst
male:
- Anxiety
- Pain
- Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
- Disturbance in attention
- Bone density decreased
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Muscle spasms (muscle contraction)
- Blood pressure increased
- Hypoaesthesia (reduced sense of touch or sensation)
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
What are the common drug interactions of Lamotrigine and Viagra, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Blood potassium decreased
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Glycosylated haemoglobin increased
- Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
- Hypoaesthesia (reduced sense of touch or sensation)
- Muscle spasms (muscle contraction)
- Obesity (having too much body fat)
- Peripheral swelling
- Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
30-39:
- Drug ineffective
- Overdose
- Priapism (prolonged and painful erection that can last from several hours up to a few days)
40-49:
- Anxiety
- Aspartate aminotransferase increased
- Confusional state
- Disturbance in attention
- Hypercalcaemia (elevated calcium (ca+) level in the blood)
- Hyperhidrosis (abnormally increased sweating)
- Hypermetabolism (abnormal increase in the body's basal metabolic rate)
- Night sweats (sweating in night)
- Petit mal epilepsy (absence seizure)
- Pain
50-59:
- Malaise (a feeling of general discomfort or uneasiness)
- Mobility decreased (ability to move is reduced)
- Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
- Multiple fractures
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Overdose
- Peripheral swelling
- Thrombosis (formation of a blood clot inside a blood vessel)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
60+:
- Fatigue (feeling of tiredness)
- Insomnia (sleeplessness)
- Initial insomnia (feeling of inadequate or poor-quality sleep)
- Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
- Pruritus (severe itching of the skin)
- Psychomotor hyperactivity (feelings of extreme restlessness)
- Sleep disorder
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Suicidal ideation
- Abdominal discomfort
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 22 people, 23.66%
- Depression: 19 people, 20.43%
- High Blood Cholesterol: 15 people, 16.13%
- Pain: 12 people, 12.90%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 12 people, 12.90%
- Hiv Infection: 11 people, 11.83%
- High Blood Pressure: 11 people, 11.83%
- Stress And Anxiety: 10 people, 10.75%
- Hypersensitivity: 7 people, 7.53%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 7.53%
* Approximation only. Some reports may have incomplete information.
Do you take Lamotrigine and Viagra?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Lamotrigine (76,638 reports)
- Viagra (63,865 reports)
Browse all drug interactions of Lamotrigine and Viagra:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lamotrigine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Viagra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lamotrigine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Viagra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
- Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
- Gupta MC, Khanna J, Mathur R, Mittal N, "Lamotrigine-induced fulminant hepatic failure: an unusual presentation", IMSEAR, 2015 Jan .
- Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
- Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
- Gupta MC, Khanna J, Mathur R, Mittal N, "Lamotrigine-induced fulminant hepatic failure: an unusual presentation", IMSEAR, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on lamotrigine and sildenafil citrate (the active ingredients of Lamotrigine and Viagra, respectively), and Lamotrigine and Viagra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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