Viagra and Pramine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Viagra (sildenafil citrate) and Pramine (imipramine hydrochloride). Common drug interactions include drug ineffective among males.
The phase IV clinical study analyzes what interactions people have when they take Viagra and Pramine. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.
What is Viagra?
Viagra has active ingredients of sildenafil citrate. It is often used in erection problems. eHealthMe is studying from 63,865 Viagra users. Check the latest studies of Viagra.
What is Pramine?
Pramine has active ingredients of imipramine hydrochloride. eHealthMe is studying from 7,461 Pramine users. Check the latest studies of Pramine.
41 people who take Viagra and Pramine together, and have interactions are studied.

What are the common drug interactions of Viagra and Pramine, by gender? *:
female:
n/a
male:
- Drug ineffective
- Bladder cancer
- Dysarthria (speech disorder)
- Multiple drug overdose intentional
- Pneumonia
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
- Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
- Therapeutic response unexpected
- Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
- Vision blurred
What are the common drug interactions of Viagra and Pramine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Acute pulmonary oedema (sudden deposit of fluid in the lung))
- Acute respiratory distress syndrome
- Atelectasis (partial or complete collapse of the lung)
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Completed suicide (act of taking one's own life)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Drug ineffective
- Multiple drug overdose intentional
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
- Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
40-49:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Renal impairment (severely reduced kidney function)
- Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
- Malignant melanoma (skin cancer rises from melancytes)
- Cardiomyopathy (weakening of the heart muscle)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Diabetes with hyperosmolarity (diabetes with increasing blood glucose levels and dehydration)
- Drug ineffective
- Renal tubular necrosis (death of kidney tubules)
50-59:
- Cystitis (inflammation of the wall of the bladder)
- Fatigue (feeling of tiredness)
- Pain
- Anaemia (lack of blood)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Ataxia (loss of full control of bodily movements)
- Balance disorder
- Blindness unilateral
- Blood phosphorus increased
60+:
- Pneumonia
- Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
- Drug ineffective
- Iiird nerve paralysis (totally closed eyelid and a down and out deviation of the eye)
- Blindness
- Hot flush (sudden feelings of heat)
- Intraocular pressure increased
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Urinary retention (the inability to completely or partially empty the bladder)
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 34.15%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 13 people, 31.71%
- High Blood Pressure: 9 people, 21.95%
- Depression: 7 people, 17.07%
- Ill-Defined Disorder: 4 people, 9.76%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 9.76%
- Stress And Anxiety: 3 people, 7.32%
- Hypersensitivity: 3 people, 7.32%
- Enlarged Prostate: 3 people, 7.32%
- Endocarditis (inflammation in heart muscle): 3 people, 7.32%
* Approximation only. Some reports may have incomplete information.
Do you take Viagra and Pramine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Viagra and Pramine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Viagra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Pramine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Viagra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pramine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
- Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on sildenafil citrate and imipramine hydrochloride (the active ingredients of Viagra and Pramine, respectively), and Viagra and Pramine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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