Rebif and Viagra drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Rebif (interferon beta-1a) and Viagra (sildenafil citrate). Common drug interactions include back disorder among females and drug ineffective among males.
The phase IV clinical study analyzes what interactions people have when they take Rebif and Viagra. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.
What is Rebif?
Rebif has active ingredients of interferon beta-1a. It is often used in multiple sclerosis. eHealthMe is studying from 61,126 Rebif users. Check the latest studies of Rebif.
What is Viagra?
Viagra has active ingredients of sildenafil citrate. It is often used in erection problems. eHealthMe is studying from 63,865 Viagra users. Check the latest studies of Viagra.
45 people who take Rebif and Viagra together, and have interactions are studied.

What are the common drug interactions of Rebif and Viagra, by gender? *:
female:
- Back disorder
- Blood creatinine increased
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
- Dependence on respirator
- Depression
- Disease progression
- Drug ineffective
- Eye disorder
- Fall
- Fatigue (feeling of tiredness)
male:
- Drug ineffective
- Fall
- Infection
- Abdominal pain
- Abnormal behaviour
- Blood pressure diastolic increased
- Confusional state
- Disease progression
- Dizziness
- Dyskinesia (abnormality or impairment of voluntary movement)
What are the common drug interactions of Rebif and Viagra, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Blood creatinine increased
- Histoplasmosis (infection caused by breathing in spores of a fungus)
- Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
- Pneumonia
30-39:
- Disease progression
- Ejection fraction decreased (systolic heart failure)
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
- Cerebellar infarction (impaired blood circulation to cerebellum)
- Dehydration (dryness resulting from the removal of water)
- Adverse drug reaction
- Carbuncle (a carbuncle is an abscess larger than a boil)
- Cellulitis (infection under the skin)
- Influenza like illness
- Injection site haemorrhage (bleeding from injection site)
40-49:
- Intervertebral disc disorder (spinal disc disorder)
- Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
- Lethargy (tiredness)
- Malaise (a feeling of general discomfort or uneasiness)
- Osteopenia (a condition where bone mineral density is lower than normal)
- Osteoporosis (bones weak and more likely to break)
- Peroneal nerve palsy
- Post laminectomy syndrome
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Spinal fracture (fracture in one of vertebrae)
50-59:
- Anaemia (lack of blood)
- Cardiac failure congestive
- Coagulopathy (blood's ability to clot is impaired)
- Hypovolaemic shock (shock caused by severe blood or fluid loss)
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
- Pulmonary oedema (fluid accumulation in the lungs)
- Renal failure acute (rapid kidney dysfunction)
- Blood pressure diastolic increased
- Dizziness
- Gastritis (inflammation of stomach)
60+:
- Drug ineffective
- Agitation (state of anxiety or nervous excitement)
- Dyskinesia (abnormality or impairment of voluntary movement)
- Dyspepsia (indigestion)
- Fatigue (feeling of tiredness)
- Feeling hot
- Hypertension (high blood pressure)
- Hyperventilation
- Injection site erythema (redness at injection site)
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
What are the existing conditions these people have? *
- Pain: 4 people, 8.89%
- Stress And Anxiety: 3 people, 6.67%
- Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 6.67%
- Gait Disturbance: 3 people, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Rebif and Viagra?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Rebif and Viagra:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Rebif:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Viagra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Rebif and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Viagra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
- Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on interferon beta-1a and sildenafil citrate (the active ingredients of Rebif and Viagra, respectively), and Rebif and Viagra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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