Unasyn and Viagra drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Unasyn (ampicillin sodium; sulbactam sodium) and Viagra (sildenafil citrate). Common drug interactions include erythema among females and anaemia among males.
The phase IV clinical study analyzes what interactions people have when they take Unasyn and Viagra. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.
What is Unasyn?
Unasyn has active ingredients of ampicillin sodium; sulbactam sodium. eHealthMe is studying from 4,474 Unasyn users. Check the latest studies of Unasyn.
What is Viagra?
Viagra has active ingredients of sildenafil citrate. It is often used in erection problems. eHealthMe is studying from 63,865 Viagra users. Check the latest studies of Viagra.
20 people who take Unasyn and Viagra together, and have interactions are studied.

What are the common drug interactions of Unasyn and Viagra, by gender? *:
female:
- Erythema (redness of the skin)
- Flushing (the warm, red condition of human skin)
- Heart rate increased
- Rash
- Rash neonatal (skin rash affecting healthy newborn babies)
male:
- Anaemia (lack of blood)
- Pain
- Calculus ureteric (stone in ureter)
- Costochondritis (chest wall pain)
- Dental caries
- Disability
- Dyspepsia (indigestion)
- Epicondylitis (tennis elbow)
- Erythema (redness of the skin)
- Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection)
What are the common drug interactions of Unasyn and Viagra, by age (0-1 to 60+)? *:
0-1:
- Erythema (redness of the skin)
- Flushing (the warm, red condition of human skin)
- Heart rate increased
- Rash
- Rash neonatal (skin rash affecting healthy newborn babies)
2-9:
n/a
10-19:
n/a
20-29:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Back pain
- Blood glucose increased
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cardiac disorder
- Cardiac failure congestive
- Coagulopathy (blood's ability to clot is impaired)
30-39:
n/a
40-49:
- Deformity (disfigurement)
- Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
- Nerve injury
- Pain
- Renal failure (kidney dysfunction)
- Renal tubular necrosis (death of kidney tubules)
- Scar
- Scrotal abscess (pus in scrotum)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Septic shock (shock due to blood infection)
50-59:
- Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
- Hepatic failure (liver failure)
- Hepatic neoplasm malignant (liver cancer)
- Hyperglycaemia (high blood sugar)
- Liver fatty (fat deposition of liver)
- Metastases to large intestine (cancer spreads to large intestine)
- Renal impairment (severely reduced kidney function)
- Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
- Anaemia (lack of blood)
- Bursitis infective staphylococcal (staphylococcal infection of the subacromial/subdeltoid bursa)
60+:
- Anaemia (lack of blood)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Dyspepsia (indigestion)
- Epicondylitis (tennis elbow)
- Erythema (redness of the skin)
- Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Gynaecomastia (enlargement of the gland tissue of the male breast)
- Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
- Hypotension (abnormally low blood pressure)
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 9 people, 45.00%
- Pain: 3 people, 15.00%
- Hypotension (abnormally low blood pressure): 3 people, 15.00%
- Type 2 Diabetes: 2 people, 10.00%
- Bipolar Disorder (mood disorder): 2 people, 10.00%
- Right Ventricular Failure (right half of the heart fails to work): 2 people, 10.00%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 10.00%
- Weight Decreased: 2 people, 10.00%
- Fungal Infection: 2 people, 10.00%
- Weight Loss: 1 person, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Unasyn and Viagra?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Unasyn and Viagra:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Unasyn:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Viagra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Unasyn and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Viagra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
- Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on ampicillin sodium; sulbactam sodium and sildenafil citrate (the active ingredients of Unasyn and Viagra, respectively), and Unasyn and Viagra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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