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Viagra and Xigduo xr drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Viagra (sildenafil citrate) and Xigduo xr (dapagliflozin propanediol; metformin hydrochloride). Common drug interactions include scrotal abscess among males.

The phase IV clinical study analyzes what interactions people have when they take Viagra and Xigduo xr. It is created by eHealthMe based on reports of 9 people who take the same drugs from the FDA, and is updated regularly.

What is Viagra?

Viagra has active ingredients of sildenafil citrate. It is often used in erection problems. eHealthMe is studying from 63,865 Viagra users. Check the latest studies of Viagra.

What is Xigduo xr?

Xigduo xr has active ingredients of dapagliflozin propanediol; metformin hydrochloride. eHealthMe is studying from 2,917 Xigduo xr users. Check the latest studies of Xigduo xr.

On Jul, 02, 2026

9 people who take Viagra and Xigduo xr together, and have interactions are studied.

Viagra and Xigduo xr drug interactions.

What are the common drug interactions of Viagra and Xigduo Xr, by gender? *:

female:

n/a

male:

  1. Scrotal abscess (pus in scrotum)
  2. Emotional distress
  3. Dysgraphia (impaired ability to learn to write)
  4. Genital abscess (build up of pus in genital)
  5. Genital lesion (sores, warts, or blemishes that appear on the genitals)
  6. Malignant melanoma (skin cancer rises from melancytes)
  7. Pain
  8. Perineal pain
  9. Proctalgia (pain in the rectum)
  10. Rectal abscess (pus in rectum)

What are the common drug interactions of Viagra and Xigduo Xr, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Scrotal abscess (pus in scrotum)
  2. Chronic kidney disease
  3. Renal impairment (severely reduced kidney function)

50-59:

  1. Anal abscess
  2. Depression
  3. Genital abscess (build up of pus in genital)
  4. Genital lesion (sores, warts, or blemishes that appear on the genitals)
  5. Pain
  6. Perineal pain
  7. Proctalgia (pain in the rectum)
  8. Rectal abscess (pus in rectum)
  9. Scrotal gangrene (death of scrotum cells)
  10. Scrotal swelling

60+:

  1. Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
  2. Drug ineffective
  3. Depression
  4. Dysgraphia (impaired ability to learn to write)
  5. Malignant melanoma (skin cancer rises from melancytes)
  6. Tremor (trembling or shaking movements in one or more parts of your body)

* Approximation only. Some reports may have incomplete information.

Do you take Viagra and Xigduo xr?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Viagra and Xigduo xr:

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Browse all side effects of Viagra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Xigduo xr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Viagra and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xigduo xr and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on sildenafil citrate and dapagliflozin propanediol; metformin hydrochloride (the active ingredients of Viagra and Xigduo xr, respectively), and Viagra and Xigduo xr (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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