Vicodin es and Atarax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vicodin es (acetaminophen; hydrocodone bitartrate) and Atarax (hydroxyzine hydrochloride). Common drug interactions include anuria among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Vicodin es and Atarax. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Vicodin es?

Vicodin es has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 2,450 Vicodin es users. Check the latest studies of Vicodin es.

What is Atarax?

Atarax has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 23,553 Atarax users. Check the latest studies of Atarax.



On Jul, 15, 2026

16 people who take Vicodin es and Atarax together, and have interactions are studied.

Vicodin es and Atarax drug interactions.

What are the common drug interactions of Vicodin Es and Atarax, by gender? *:

female:

  1. Anuria (failure of the kidneys to produce urine)
  2. Blood uric acid increased
  3. Coma (state of unconsciousness lasting more than six hours)
  4. Disseminated intravascular coagulation (systemic activation of blood coagulation)
  5. Hepatic necrosis (large portions of liver die off due to severe liver disease)
  6. Hypercholesterolaemia (high levels of cholesterol in the blood)
  7. Hypertriglyceridaemia (excess of triglycerides in the blood)
  8. Hypotension (abnormally low blood pressure)
  9. Hypoxia (low oxygen in tissues)
  10. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)

male:

  1. Drug ineffective
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  4. Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
  5. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  6. Coma (state of unconsciousness lasting more than six hours)
  7. Gallbladder disorder
  8. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  9. Haematemesis (vomiting of blood)
  10. Hyperpyrexia (extremely high fever)

What are the common drug interactions of Vicodin Es and Atarax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Cardiac arrest
  2. Multiple drug overdose
  3. Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)

40-49:

  1. Blood calcium decreased
  2. Blood potassium increased
  3. Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
  4. Coma (state of unconsciousness lasting more than six hours)
  5. Gallbladder disorder
  6. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  7. Haematemesis (vomiting of blood)
  8. Hyperpyrexia (extremely high fever)
  9. Hypertension (high blood pressure)
  10. International normalised ratio increased

50-59:

  1. Hepatic necrosis (large portions of liver die off due to severe liver disease)
  2. Hypercholesterolaemia (high levels of cholesterol in the blood)
  3. Hypertriglyceridaemia (excess of triglycerides in the blood)
  4. Hypotension (abnormally low blood pressure)
  5. Hypoxia (low oxygen in tissues)
  6. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
  7. Liver fatty (fat deposition of liver)
  8. Multi-organ failure (multisystem organ failure)
  9. Oedema (fluid collection in tissue)
  10. Pancreatitis acute (sudden inflammation of pancreas)

60+:

  1. Drug ineffective
  2. Ageusia (loss of taste functions of the tongue)
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  4. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  5. Irritability
  6. Somnolence (a state of near-sleep, a strong desire for sleep)

What are the existing conditions these people have? *

  1. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 3 people, 18.75%
  2. Asthma: 2 people, 12.50%
  3. Cardiac Failure Congestive: 2 people, 12.50%
  4. Dyspnea (difficult or laboured breathing): 2 people, 12.50%
  5. Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 1 person, 6.25%
  6. Swelling: 1 person, 6.25%
  7. Chronic Fatigue Syndrome (disorder that causes extreme fatigue): 1 person, 6.25%
  8. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 6.25%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.25%
  10. Gout (uric acid crystals building up in the body): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vicodin es and Atarax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vicodin es:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Atarax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vicodin es and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Atarax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; hydrocodone bitartrate and hydroxyzine hydrochloride (the active ingredients of Vicodin es and Atarax, respectively), and Vicodin es and Atarax (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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