Vicodin and Bifido drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vicodin (acetaminophen; hydrocodone bitartrate) and Bifido (bifidobacteria). Common drug interactions include fatigue among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Vicodin and Bifido. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Vicodin?

Vicodin has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 63,357 Vicodin users. Check the latest studies of Vicodin.

What is Bifido?

Bifido has active ingredients of bifidobacteria. eHealthMe is studying from 5,030 Bifido users. Check the latest studies of Bifido.



On Jul, 10, 2026

17 people who take Vicodin and Bifido together, and have interactions are studied.

Vicodin and Bifido drug interactions.

What are the common drug interactions of Vicodin and Bifido, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Nausea (feeling of having an urge to vomit)
  3. Abdominal discomfort
  4. Abdominal pain upper
  5. Depressed mood
  6. Muscle spasms (muscle contraction)
  7. Myalgia (muscle pain)
  8. Rash
  9. Abdominal distension
  10. Alopecia (absence of hair from areas of the body)

male:

  1. Diarrhoea
  2. Respiratory distress (difficulty in breathing)
  3. Infection
  4. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  5. Vitamin d decreased
  6. Cataract (clouding of the lens inside the eye)
  7. Constipation
  8. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
  9. Eye disorder
  10. Furuncle (infection of the hair follicle)

What are the common drug interactions of Vicodin and Bifido, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Anxiety
  2. Oedema peripheral (superficial swelling)
  3. Trigeminal nerve disorder (disease of facial nerve)

50-59:

  1. Abdominal discomfort
  2. Abdominal distension
  3. Abdominal pain upper
  4. Alopecia (absence of hair from areas of the body)
  5. Asthenia (weakness)
  6. Back injury
  7. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  8. Concussion (short loss of normal brain function in response to a head injury)
  9. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
  10. Depressed mood

60+:

  1. Diarrhoea
  2. Nausea (feeling of having an urge to vomit)
  3. Cystitis (inflammation of the wall of the bladder)
  4. Cytomegalovirus colitis (an inflammation of the colon from virus)
  5. Dementia alzheimer's type (loss of mental ability with alzheimer's symptom)
  6. Depression
  7. Drug ineffective
  8. Dyspepsia (indigestion)
  9. Eye disorder
  10. Faeces discoloured

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 4 people, 23.53%
  2. Diarrhea: 2 people, 11.76%
  3. Immunodeficiency Common Variable: 2 people, 11.76%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 11.76%
  5. Embolism (obstruction of an artery, typically by a clot of blood or an air bubble): 1 person, 5.88%
  6. Headache (pain in head): 1 person, 5.88%
  7. Gastric Ulcer (stomach ulcer): 1 person, 5.88%
  8. Gait Disturbance: 1 person, 5.88%
  9. Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 1 person, 5.88%
  10. High Blood Pressure: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Vicodin and Bifido?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vicodin and Bifido:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vicodin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Bifido:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vicodin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bifido and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; hydrocodone bitartrate and bifidobacteria (the active ingredients of Vicodin and Bifido, respectively), and Vicodin and Bifido (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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