Vicodin and Crixivan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vicodin (acetaminophen; hydrocodone bitartrate) and Crixivan (indinavir sulfate). Common drug interactions include gastrointestinal haemorrhage among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Vicodin and Crixivan. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Vicodin?

Vicodin has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 63,357 Vicodin users. Check the latest studies of Vicodin.

What is Crixivan?

Crixivan has active ingredients of indinavir sulfate. eHealthMe is studying from 6,312 Crixivan users. Check the latest studies of Crixivan.

On Jul, 21, 2026

48 people who take Vicodin and Crixivan together, and have interactions are studied.

What are the common drug interactions of Vicodin and Crixivan, by gender? *:

female:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hypersensitivity
Neuropathy (damage to nerves)
Polyuria (production of too much dilute urine)
Syncope (loss of consciousness with an inability to maintain postural tone)
Tongue disorder (disease of tongue)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Blood pressure increased
Cyst (a closed sac)
Dyspnoea (difficult or laboured respiration)

male:

Dyspnoea (difficult or laboured respiration)
Dehydration (dryness resulting from the removal of water)
Hydronephrosis (water inside the kidney)
Impaired gastric emptying
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Kaposi's sarcoma (a tumour caused by human herpes virus)
Liver fatty (fat deposition of liver)
Oedema (fluid collection in tissue)
Oedema lower limb (fluid collection in tissue of lower leg)
Oesophagitis (inflammation of oesophagus)

What are the common drug interactions of Vicodin and Crixivan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Chest pain
Dehydration (dryness resulting from the removal of water)
Dyspnoea (difficult or laboured respiration)
Hydronephrosis (water inside the kidney)
Vomiting
Abdominal pain
Blood albumin decreased
Diarrhoea
Hepatosplenomegaly (enlargement of both the liver and the spleen)
Oesophageal ulcer (ulcer of oesophagus)

30-39:

Loin pain (pain originates from kidney)
Nausea (feeling of having an urge to vomit)
Vomiting
Blood culture positive
Blood ph decreased
Dyspnoea (difficult or laboured respiration)
Dysuria (painful or difficult urination)
Hepatic failure (liver failure)
Hydronephrosis (water inside the kidney)
Hypercapnia (too much smoke)

40-49:

Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Urobilinuria present
Aseptic necrosis bone
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Back injury
Blood triglycerides increased
Blood urea increased
Diarrhoea
Dizziness

50-59:

Angina pectoris (chest pain due to ischemia of the heart muscle)
Blood cholesterol increased
Blood triglycerides increased
Chest pain
Coma (state of unconsciousness lasting more than six hours)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Pyrexia (fever)

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Intervertebral disc protrusion (spinal disc protrusion)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteonecrosis (death of bone)
Osteoporosis (bones weak and more likely to break)
Renal failure (kidney dysfunction)
Spinal osteoarthritis (joint cartilage loss in spine)
Tooth fracture
Vertebral foraminal stenosis (narrowing of the intervertebral foramen)

* Approximation only. Some reports may have incomplete information.

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