Vicodin and Licorice drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vicodin (acetaminophen; hydrocodone bitartrate) and Licorice (licorice). Common drug interactions include depression among females.

The phase IV clinical study analyzes what interactions people have when they take Vicodin and Licorice. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Vicodin?

Vicodin has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 63,357 Vicodin users. Check the latest studies of Vicodin.

What is Licorice?

Licorice has active ingredients of licorice. eHealthMe is studying from 420 Licorice users. Check the latest studies of Licorice.

On Jul, 11, 2026

22 people who take Vicodin and Licorice together, and have interactions are studied.

What are the common drug interactions of Vicodin and Licorice, by gender? *:

female:

Depression
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Abdominal distension
Abdominal hernia
Abdominal mass (localized enlargement or swelling in the human abdomen)
Abdominal pain lower
Abdominal wall abscess (abdominal wall infection)
Abscess (pus)
Brain neoplasm (tumour of brain)
Chills (felling of cold)

male:

n/a

What are the common drug interactions of Vicodin and Licorice, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
Ovarian cyst (fluid filled sac of the ovary)

40-49:

Depression
Suicidal ideation
Anxiety
Insomnia (sleeplessness)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Sedation
Somnolence (a state of near-sleep, a strong desire for sleep)
Accident
Brain neoplasm (tumour of brain)
Headache (pain in head)

50-59:

Abdominal distension
Abdominal hernia
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Dizziness
Fatigue (feeling of tiredness)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hydronephrosis (water inside the kidney)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Immunosuppression

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 19 people, 86.36%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 27.27%
Depression: 4 people, 18.18%
Stress And Anxiety: 2 people, 9.09%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 9.09%
Muscle Spasms (muscle contraction): 2 people, 9.09%
Joint Pain: 2 people, 9.09%
Back Pain: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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