Vicodin and Mavik drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vicodin (acetaminophen; hydrocodone bitartrate) and Mavik (trandolapril). Common drug interactions include coronary artery disease among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Vicodin and Mavik. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Vicodin?

Vicodin has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 63,357 Vicodin users. Check the latest studies of Vicodin.

What is Mavik?

Mavik has active ingredients of trandolapril. It is often used in high blood pressure. eHealthMe is studying from 3,145 Mavik users. Check the latest studies of Mavik.

On Jul, 15, 2026

34 people who take Vicodin and Mavik together, and have interactions are studied.

What are the common drug interactions of Vicodin and Mavik, by gender? *:

female:

Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Hyperlipidaemia (presence of excess lipids in the blood)
Ovarian disorder (disease of ovary)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Anxiety
Emotional distress
Nausea (feeling of having an urge to vomit)
Sinus bradycardia (an unusually slow heartbeat due to heart disease)
Ventricular hypertrophy (enlargement of ventricles (lower chambers) in the heart)
Abdominal pain

male:

Dizziness
Headache (pain in head)
Drug tolerance increased
Pain in extremity
Pancreatitis acute (sudden inflammation of pancreas)
Rash
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Dyspnoea exertional (breathlessness or shortness of breath)
Mitral valve incompetence (inefficient heart valve)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

What are the common drug interactions of Vicodin and Mavik, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Depression
Chest pain
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Diarrhoea
Drug addiction
Drug dependence
Drug tolerance increased
Headache (pain in head)
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)

50-59:

Cardiomyopathy (weakening of the heart muscle)
Catheter site infection (infection at the site of insertion)
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Diabetic ulcer
Diarrhoea
Dyspnoea paroxysmal nocturnal (respiratory distress that awakens patients from sleep)
Emotional distress
Fall
Fear
Hyperglycaemia (high blood sugar)

60+:

Dizziness
Arthralgia (joint pain)
Injury
Mitral valve incompetence (inefficient heart valve)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Oedema peripheral (superficial swelling)
Pain in extremity
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Sensory loss (senses loss)
Tricuspid valve incompetence (inefficient heart valve)

What are the existing conditions these people have? *

Thyroid Diseases: 5 people, 14.71%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 5 people, 14.71%
Glaucoma (increased fluid pressure in the eye with vision loss): 5 people, 14.71%
Osteoporosis (bones weak and more likely to break): 2 people, 5.88%
Muscle Strain (an injury to a muscle in which the muscle fibres tear): 2 people, 5.88%
Gout (uric acid crystals building up in the body): 2 people, 5.88%
Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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