Vicodin and Mitoxantrone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vicodin (acetaminophen; hydrocodone bitartrate) and Mitoxantrone (mitoxantrone hydrochloride). Common drug interactions include alopecia among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Vicodin and Mitoxantrone. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Vicodin?

Vicodin has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 63,357 Vicodin users. Check the latest studies of Vicodin.

What is Mitoxantrone?

Mitoxantrone has active ingredients of mitoxantrone hydrochloride. eHealthMe is studying from 8,125 Mitoxantrone users. Check the latest studies of Mitoxantrone.



On Jul, 08, 2026

14 people who take Vicodin and Mitoxantrone together, and have interactions are studied.

Vicodin and Mitoxantrone drug interactions.

What are the common drug interactions of Vicodin and Mitoxantrone, by gender? *:

female:

  1. Alopecia (absence of hair from areas of the body)
  2. Anxiety
  3. Hair colour changes
  4. Hair disorder
  5. Stress
  6. Abdominal distension
  7. Coccydynia (pain in the coccyx or tailbone area)
  8. Dyspnoea (difficult or laboured respiration)
  9. Neoplasm progression (growth of tumour)
  10. Oedema peripheral (superficial swelling)

male:

  1. Anaemia (lack of blood)
  2. Bone disorder
  3. Pelvic pain
  4. Syncope (loss of consciousness with an inability to maintain postural tone)
  5. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
  6. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  7. Anxiety
  8. Blood homocysteine increased
  9. Blood pressure increased
  10. Cerebral infarction (less blood supply to brain resulting tissue damage)

What are the common drug interactions of Vicodin and Mitoxantrone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Anaemia (lack of blood)
  2. Blood pressure increased
  3. Chills (felling of cold)
  4. Death
  5. Disease progression
  6. Dizziness
  7. Dyspnoea (difficult or laboured respiration)
  8. Fatigue (feeling of tiredness)
  9. Meningitis bacterial (bacterial inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
  10. Nausea (feeling of having an urge to vomit)

50-59:

  1. Anaemia (lack of blood)
  2. Disease progression
  3. Dyspnoea exertional (breathlessness or shortness of breath)
  4. Fatigue (feeling of tiredness)
  5. Heart rate irregular
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Metastasis (spreadable cancer to other organ from origin)
  8. Muscle spasms (muscle contraction)
  9. Night sweats (sweating in night)
  10. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

60+:

  1. Bone disorder
  2. Constipation
  3. Hair disorder
  4. Pelvic pain
  5. Stress
  6. Syncope (loss of consciousness with an inability to maintain postural tone)
  7. Blood homocysteine increased
  8. Cerebral infarction (less blood supply to brain resulting tissue damage)
  9. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  10. Dysarthria (speech disorder)

What are the existing conditions these people have? *

  1. Prostate Cancer: 4 people, 28.57%
  2. Metastases To Bone (cancer spreads to bone): 3 people, 21.43%
  3. Breast Cancer Female: 3 people, 21.43%
  4. Prostate Cancer Metastatic: 1 person, 7.14%
  5. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 7.14%
  6. Breast Cancer Metastatic: 1 person, 7.14%
  7. Breast Cancer: 1 person, 7.14%
  8. Body Temperature Increased: 1 person, 7.14%
  9. Acute Promyelocytic Leukaemia (cancer of the blood and bone marrow): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Vicodin and Mitoxantrone?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vicodin and Mitoxantrone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vicodin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Mitoxantrone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vicodin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mitoxantrone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; hydrocodone bitartrate and mitoxantrone hydrochloride (the active ingredients of Vicodin and Mitoxantrone, respectively), and Vicodin and Mitoxantrone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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