Vicodin and Rocuronium bromide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vicodin (acetaminophen; hydrocodone bitartrate) and Rocuronium bromide (rocuronium bromide). Common drug interactions include post procedural complication among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Vicodin and Rocuronium bromide. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Vicodin?

Vicodin has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 63,357 Vicodin users. Check the latest studies of Vicodin.

What is Rocuronium bromide?

Rocuronium bromide has active ingredients of rocuronium bromide. eHealthMe is studying from 5,615 Rocuronium bromide users. Check the latest studies of Rocuronium bromide.



On Jul, 10, 2026

16 people who take Vicodin and Rocuronium bromide together, and have interactions are studied.

Vicodin and Rocuronium bromide drug interactions.

What are the common drug interactions of Vicodin and Rocuronium Bromide, by gender? *:

female:

  1. Post procedural complication
  2. Procedural pain
  3. Spinal fracture (fracture in one of vertebrae)
  4. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  5. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  6. Blood pressure decreased
  7. Cholecystitis chronic (long lasting infection of gallbladder)
  8. Electrocardiogram st segment depression
  9. Hypotension (abnormally low blood pressure)
  10. Injury

male:

  1. Renal failure (kidney dysfunction)
  2. Renal injury (kidney injury)
  3. Cardiac failure
  4. Death
  5. Heart valve incompetence (heart's valves do not work correctly)
  6. Pulmonary hypertension (increase in blood pressure in the lung artery)
  7. Renal failure chronic (long lasting kidney dysfunction)
  8. Angina pectoris (chest pain due to ischemia of the heart muscle)
  9. Arthralgia (joint pain)
  10. Asthenia (weakness)

What are the common drug interactions of Vicodin and Rocuronium Bromide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Post procedural complication
  2. Procedural pain
  3. Spinal fracture (fracture in one of vertebrae)
  4. Cholecystitis chronic (long lasting infection of gallbladder)
  5. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  6. Portal vein thrombosis (venous thrombosis affecting the hepatic portal vein)

30-39:

  1. Blood pressure decreased
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Electrocardiogram st segment depression
  4. Injury
  5. Pulmonary embolism (blockage of the main artery of the lung)
  6. Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)

40-49:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Death
  4. Emotional distress
  5. Fear
  6. Injury
  7. Renal failure (kidney dysfunction)
  8. Renal failure acute (rapid kidney dysfunction)
  9. Renal impairment (severely reduced kidney function)
  10. Renal injury (kidney injury)

50-59:

  1. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  2. Renal failure (kidney dysfunction)
  3. Renal injury (kidney injury)
  4. Angina pectoris (chest pain due to ischemia of the heart muscle)
  5. Arthralgia (joint pain)
  6. Asthenia (weakness)
  7. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  8. Cardiac arrest
  9. Cardioactive drug level increased
  10. Chest discomfort

60+:

  1. Renal failure (kidney dysfunction)
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Heart valve incompetence (heart's valves do not work correctly)
  4. Pulmonary hypertension (increase in blood pressure in the lung artery)
  5. Renal failure chronic (long lasting kidney dysfunction)
  6. Multi-organ failure (multisystem organ failure)
  7. Psychiatric symptom
  8. Tachyarrhythmia (disturbance of the heart rhythm in which the heart rate is abnormally increased)
  9. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  10. Death

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 31.25%
  2. Anaesthesia: 4 people, 25.00%
  3. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 3 people, 18.75%
  4. Stress And Anxiety: 2 people, 12.50%
  5. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 2 people, 12.50%
  6. Seasonal Allergy (allergic condition due to certain season): 2 people, 12.50%
  7. Headache (pain in head): 2 people, 12.50%
  8. High Blood Cholesterol: 2 people, 12.50%
  9. High Blood Pressure: 2 people, 12.50%
  10. Blood Pressure Abnormal: 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vicodin and Rocuronium bromide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vicodin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Rocuronium bromide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vicodin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rocuronium bromide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; hydrocodone bitartrate and rocuronium bromide (the active ingredients of Vicodin and Rocuronium bromide, respectively), and Vicodin and Rocuronium bromide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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