Vicoprofen and Aldactone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vicoprofen (hydrocodone bitartrate; ibuprofen) and Aldactone (spironolactone). Common drug interactions include arthralgia among females and oedema peripheral among males.

The phase IV clinical study analyzes what interactions people have when they take Vicoprofen and Aldactone. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Vicoprofen?

Vicoprofen has active ingredients of hydrocodone bitartrate; ibuprofen. It is often used in pain. eHealthMe is studying from 1,842 Vicoprofen users. Check the latest studies of Vicoprofen.

What is Aldactone?

Aldactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 46,063 Aldactone users. Check the latest studies of Aldactone.

On Jul, 09, 2026

17 people who take Vicoprofen and Aldactone together, and have interactions are studied.

Vicoprofen and Aldactone drug interactions.

What are the common drug interactions of Vicoprofen and Aldactone, by gender? *:

female:

Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Arthropathy
Asthenia (weakness)
Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
Atrioventricular block first degree (heart block first degree)
Balance disorder
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Blood albumin decreased
Blood glucose decreased

male:

Oedema peripheral (superficial swelling)
Arthralgia (joint pain)
Anxiety
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Balance disorder
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Blood glucose decreased
Blood pressure fluctuation
Blood urea increased
Bone disorder

What are the common drug interactions of Vicoprofen and Aldactone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cellulitis (infection under the skin)
Dry skin
Night sweats (sweating in night)
Oedema peripheral (superficial swelling)

40-49:

Aortic arch syndrome (structural problems in the arteries that branch off the aortic arch)
Mesenteric artery embolism (blockage in mesenteric artery by blood clot)
Thromboembolism (obstruction of artery by blood clot)

50-59:

Anaemia (lack of blood)
Arthropathy
Blood iron decreased
Dental discomfort
Haematocrit decreased
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

60+:

Agitation (state of anxiety or nervous excitement)
Alanine aminotransferase decreased
Blood urea increased
Bone disorder
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Cataract (clouding of the lens inside the eye)
Confusional state
Constipation
Deafness
Decreased interest

What are the existing conditions these people have? *

Prostate Cancer: 12 people, 70.59%
Metastases To Bone (cancer spreads to bone): 12 people, 70.59%
Hyperkalemia (damage to or disease of the kidney): 1 person, 5.88%
Bipolar Disorder (mood disorder): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Vicoprofen and Aldactone?

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