Videx and Vioxx drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Videx (didanosine) and Vioxx (rofecoxib). Common drug interactions include pancreatitis among females and acquired immunodeficiency syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Videx and Vioxx. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Videx?

Videx has active ingredients of didanosine. eHealthMe is studying from 7,927 Videx users. Check the latest studies of Videx.

What is Vioxx?

Vioxx has active ingredients of rofecoxib. It is often used in arthritis. eHealthMe is studying from 110,130 Vioxx users. Check the latest studies of Vioxx.

On Jul, 09, 2026

23 people who take Videx and Vioxx together, and have interactions are studied.

What are the common drug interactions of Videx and Vioxx, by gender? *:

female:

Pancreatitis (inflammation of pancreas)
Chest pain
Haemangioma of liver (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in liver)
Herpes simplex (herpes simplex is a common viral infection)
Pre-eclampsia (high blood pressure and significant amounts of protein in the urine of a pregnant woman)
Pregnancy
Premature delivery
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Blood glucose increased
Blood lactic acid increased

male:

Acquired immunodeficiency syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv))
Blood creatine phosphokinase increased
Necrotising colitis (inflammation in the intestines (usually the colon) that can be life-threatening)
Premature baby
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Diabetes mellitus non-insulin-dependent
Pancreatitis (inflammation of pancreas)
Parotitis (inflammation of a parotid gland)
Ventricular hypertrophy (enlargement of ventricles (lower chambers) in the heart)
Gallbladder cancer

What are the common drug interactions of Videx and Vioxx, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Pancreatitis (inflammation of pancreas)
Haemangioma of liver (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in liver)
Blood glucose increased
Blood lactic acid increased
Acquired immunodeficiency syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv))
Anxiety
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Polytraumatism (multiple trauma)

50-59:

Chest pain
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Acquired immunodeficiency syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv))
Coma (state of unconsciousness lasting more than six hours)
Diabetes mellitus non-insulin-dependent
Dyspnoea (difficult or laboured respiration)
Pancreatitis (inflammation of pancreas)
Parotitis (inflammation of a parotid gland)

60+:

Blood creatine phosphokinase increased
Blood disorder
Pre-eclampsia (high blood pressure and significant amounts of protein in the urine of a pregnant woman)
Pregnancy
Premature baby
Premature delivery
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Gallbladder cancer
Jaundice cholestatic
Rectal cancer (cancer of rectum)

What are the existing conditions these people have? *

Hiv Infection: 5 people, 21.74%
Depression: 3 people, 13.04%
Constipation: 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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