Vigamox and Norco drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vigamox (moxifloxacin hydrochloride) and Norco (acetaminophen; hydrocodone bitartrate). Common drug interactions include abdominal pain upper among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Vigamox and Norco. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Vigamox?

Vigamox has active ingredients of moxifloxacin hydrochloride. It is often used in conjunctivitis. eHealthMe is studying from 2,899 Vigamox users. Check the latest studies of Vigamox.

What is Norco?

Norco has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 74,063 Norco users. Check the latest studies of Norco.



On Jul, 06, 2026

35 people who take Vigamox and Norco together, and have interactions are studied.

Vigamox and Norco drug interactions.

What are the common drug interactions of Vigamox and Norco, by gender? *:

female:

  1. Abdominal pain upper
  2. Abnormal dreams
  3. Adverse drug reaction
  4. Alopecia (absence of hair from areas of the body)
  5. Anxiety
  6. Arthralgia (joint pain)
  7. Atrophic vulvovaginitis (inflammation of the vulva)
  8. Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
  9. Breast cancer
  10. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)

male:

  1. Chronic kidney disease
  2. Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
  3. Thrombosis (formation of a blood clot inside a blood vessel)
  4. Depression
  5. Neuropathy peripheral (surface nerve damage)
  6. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  7. Anxiety
  8. Death
  9. Emotional distress
  10. Fatigue (feeling of tiredness)

What are the common drug interactions of Vigamox and Norco, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Blood creatinine increased
  4. Chronic kidney disease
  5. Emotional distress
  6. Fatigue (feeling of tiredness)
  7. Gout (uric acid crystals building up in the body)
  8. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  9. Renal impairment (severely reduced kidney function)

40-49:

  1. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Renal failure (kidney dysfunction)
  4. Blood pressure decreased
  5. Dehydration (dryness resulting from the removal of water)
  6. Eye haemorrhage (bleeding in the eye)
  7. Eye pruritus (eye itching)
  8. Heart rate decreased
  9. Hypertension (high blood pressure)
  10. Infection

50-59:

  1. Renal failure (kidney dysfunction)
  2. Hospitalisation
  3. Hypoxia (low oxygen in tissues)
  4. Chronic kidney disease
  5. Nephrogenic anaemia (anaemia due to kidney disease)
  6. Renal impairment (severely reduced kidney function)
  7. Renal injury (kidney injury)

60+:

  1. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  2. Pleural effusion (water on the lungs)
  3. Renal impairment (severely reduced kidney function)
  4. Abdominal pain
  5. Arthralgia (joint pain)
  6. Cardiac failure congestive
  7. Chest discomfort
  8. Cough
  9. Death
  10. Depression

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 14.29%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 11.43%
  3. Insomnia (sleeplessness): 4 people, 11.43%
  4. Depression: 4 people, 11.43%
  5. Indigestion: 4 people, 11.43%
  6. Multiple Myeloma (cancer of the plasma cells): 4 people, 11.43%
  7. High Blood Pressure: 3 people, 8.57%
  8. Hypercalcaemia (elevated calcium (ca+) level in the blood): 3 people, 8.57%
  9. Diabetes: 3 people, 8.57%
  10. Hypotension (abnormally low blood pressure): 3 people, 8.57%

* Approximation only. Some reports may have incomplete information.

Do you take Vigamox and Norco?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vigamox and Norco:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vigamox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Norco:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vigamox and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Norco and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on moxifloxacin hydrochloride and acetaminophen; hydrocodone bitartrate (the active ingredients of Vigamox and Norco, respectively), and Vigamox and Norco (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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