Vigamox and Septra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vigamox (moxifloxacin hydrochloride) and Septra (sulfamethoxazole; trimethoprim). Common drug interactions include cholecystitis chronic among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Vigamox and Septra. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Vigamox?

Vigamox has active ingredients of moxifloxacin hydrochloride. It is often used in conjunctivitis. eHealthMe is studying from 2,899 Vigamox users. Check the latest studies of Vigamox.

What is Septra?

Septra has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 10,280 Septra users. Check the latest studies of Septra.



On Jul, 31, 2026

12 people who take Vigamox and Septra together, and have interactions are studied.

Vigamox and Septra drug interactions.

What are the common drug interactions of Vigamox and Septra, by gender? *:

female:

  1. Cholecystitis chronic (long lasting infection of gallbladder)
  2. Grand mal convulsion (a type of generalized seizure that affects the entire brain)
  3. Death
  4. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  5. Anxiety
  6. Chronic kidney disease
  7. Emotional distress
  8. Eye infection
  9. Hyperkalaemia (damage to or disease of the kidney)
  10. Multiple fractures

male:

  1. Pneumonia
  2. Respiratory failure (inadequate gas exchange by the respiratory system)
  3. Anaphylactic reaction (serious allergic reaction)

What are the common drug interactions of Vigamox and Septra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Anaphylactic reaction (serious allergic reaction)

10-19:

n/a

20-29:

  1. Cardiac failure congestive
  2. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  3. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  4. Grand mal convulsion (a type of generalized seizure that affects the entire brain)
  5. Haemolytic uraemic syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more)
  6. Hypertension (high blood pressure)
  7. Nephrolithiasis (calculi in the kidneys)
  8. Renal failure (kidney dysfunction)
  9. Cholecystitis chronic (long lasting infection of gallbladder)

30-39:

n/a

40-49:

n/a

50-59:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Emotional distress
  4. Multiple fractures
  5. Osteoporosis (bones weak and more likely to break)
  6. Pain
  7. Death
  8. Gait disturbance
  9. General physical health deterioration (weak health status)

60+:

  1. Chronic kidney disease
  2. Death
  3. Hypertensive nephropathy (hypertensive renal disease)
  4. Incontinence (lack of moderation or self-control)
  5. Micturition urgency (urgency to pass the urine)
  6. Nephropathy (damage to or disease of a kidney)
  7. Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
  8. Polyuria (production of too much dilute urine)
  9. Proteinuria (presence of protein in the urine)
  10. Pyelocaliectasis

What are the existing conditions these people have? *

  1. Pain: 10 people, 83.33%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 75.00%
  3. Thyroid Diseases: 7 people, 58.33%
  4. Stress And Anxiety: 7 people, 58.33%
  5. Depression: 7 people, 58.33%
  6. Blood Pressure Abnormal: 6 people, 50.00%
  7. Parathyroid Disorder: 5 people, 41.67%
  8. Blood Phosphorus Increased: 5 people, 41.67%
  9. Immune System Disorder: 5 people, 41.67%
  10. Acute Kidney Failure: 5 people, 41.67%

* Approximation only. Some reports may have incomplete information.

Do you take Vigamox and Septra?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vigamox and Septra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vigamox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Septra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vigamox and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Septra and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on moxifloxacin hydrochloride and sulfamethoxazole; trimethoprim (the active ingredients of Vigamox and Septra, respectively), and Vigamox and Septra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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