Viibryd and Hetlioz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Viibryd (vilazodone hydrochloride) and Hetlioz (tasimelteon). Common drug interactions include initial insomnia among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Viibryd and Hetlioz. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Viibryd?

Viibryd has active ingredients of vilazodone hydrochloride. It is often used in depression. eHealthMe is studying from 11,106 Viibryd users. Check the latest studies of Viibryd.

What is Hetlioz?

Hetlioz has active ingredients of tasimelteon. eHealthMe is studying from 7,418 Hetlioz users. Check the latest studies of Hetlioz.

On Jul, 18, 2026

30 people who take Viibryd and Hetlioz together, and have interactions are studied.

What are the common drug interactions of Viibryd and Hetlioz, by gender? *:

female:

Initial insomnia (feeling of inadequate or poor-quality sleep)
Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Drug ineffective
Insomnia (sleeplessness)
Sleep disorder
Coma (state of unconsciousness lasting more than six hours)
Asthenia (weakness)
Depressed mood
Fatigue (feeling of tiredness)
Drug hypersensitivity

male:

Drug ineffective
Sinus disorder (disease of sinus)
Insomnia (sleeplessness)
Paranasal sinus discomfort
Paranasal sinus hypersecretion
Sinus pain
Abdominal pain upper
Death
Malaise (a feeling of general discomfort or uneasiness)
Umbilical hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button)

What are the common drug interactions of Viibryd and Hetlioz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Drug ineffective

30-39:

Sinus disorder (disease of sinus)
Coma (state of unconsciousness lasting more than six hours)

40-49:

Initial insomnia (feeling of inadequate or poor-quality sleep)
Insomnia (sleeplessness)
Sleep disorder
Abdominal pain upper
Drug ineffective
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)

50-59:

Tension headache
Drug ineffective
Umbilical hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button)
Weight decreased
Diarrhoea
Impaired gastric emptying
Nausea (feeling of having an urge to vomit)

60+:

Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Asthenia (weakness)
Depressed mood
Fatigue (feeling of tiredness)
Initial insomnia (feeling of inadequate or poor-quality sleep)
Insomnia (sleeplessness)
Drug ineffective

What are the existing conditions these people have? *

Circadian Rhythm Sleep Disorder (family of sleep disorders affecting, among other things, the timing of sleep): 8 people, 26.67%
Stress And Anxiety: 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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