Viibryd and Imdur drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Viibryd (vilazodone hydrochloride) and Imdur (isosorbide mononitrate). Common drug interactions include coronary artery occlusion among females and drug hypersensitivity among males.

The phase IV clinical study analyzes what interactions people have when they take Viibryd and Imdur. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Viibryd?

Viibryd has active ingredients of vilazodone hydrochloride. It is often used in depression. eHealthMe is studying from 11,106 Viibryd users. Check the latest studies of Viibryd.

What is Imdur?

Imdur has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 17,367 Imdur users. Check the latest studies of Imdur.



On Jul, 13, 2026

19 people who take Viibryd and Imdur together, and have interactions are studied.

Viibryd and Imdur drug interactions.

What are the common drug interactions of Viibryd and Imdur, by gender? *:

female:

  1. Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
  2. Dyspnoea (difficult or laboured respiration)
  3. Fall
  4. Humerus fracture (injury to the upper arm bone)
  5. Loss of consciousness
  6. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  7. Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
  8. Confusional state
  9. Headache (pain in head)
  10. Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)

male:

  1. Drug hypersensitivity
  2. Cardiac failure
  3. Bankruptcy
  4. Homeless
  5. Injury
  6. Knee arthroplasty
  7. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  8. Mitral valve incompetence (inefficient heart valve)
  9. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  10. Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)

What are the common drug interactions of Viibryd and Imdur, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Diarrhoea
  2. Hallucination (an experience involving the perception of something not present)
  3. Tremor (trembling or shaking movements in one or more parts of your body)
  4. Acute left ventricular failure (heart attack)
  5. Acute myocardial infarction (acute heart attack)
  6. Blood methanol increased
  7. Cardiac failure
  8. Cardiac failure congestive
  9. Cardiovascular disorder (heart diseases)
  10. Headache (pain in head)

50-59:

  1. Drug hypersensitivity
  2. Fall
  3. Humerus fracture (injury to the upper arm bone)
  4. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  5. Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
  6. Confusional state
  7. Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
  8. Dyspnoea (difficult or laboured respiration)
  9. Loss of consciousness
  10. Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)

60+:

  1. Ataxia (loss of full control of bodily movements)
  2. Blood creatine phosphokinase increased
  3. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  4. Nystagmus (a condition of involuntary eye movement)
  5. Osteoporosis (bones weak and more likely to break)
  6. Renal impairment (severely reduced kidney function)
  7. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  8. Somnolence (a state of near-sleep, a strong desire for sleep)
  9. Vision blurred
  10. Vomiting

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 31.58%
  2. Diabetes: 6 people, 31.58%
  3. Pain: 4 people, 21.05%
  4. Chest Pain: 3 people, 15.79%
  5. Stable Angina (a constant chest pain): 3 people, 15.79%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 15.79%
  7. Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 2 people, 10.53%
  8. High Blood Cholesterol: 2 people, 10.53%
  9. Nausea (feeling of having an urge to vomit): 2 people, 10.53%
  10. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

Do you take Viibryd and Imdur?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Viibryd and Imdur:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Viibryd:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Imdur:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Viibryd and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Imdur and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on vilazodone hydrochloride and isosorbide mononitrate (the active ingredients of Viibryd and Imdur, respectively), and Viibryd and Imdur (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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