Vimovo and Ambien drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vimovo (esomeprazole magnesium; naproxen) and Ambien (zolpidem tartrate). Common drug interactions include chronic kidney disease among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Vimovo and Ambien. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Vimovo?

Vimovo has active ingredients of esomeprazole magnesium; naproxen. It is often used in osteoarthritis. eHealthMe is studying from 9,608 Vimovo users. Check the latest studies of Vimovo.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.

On Jul, 21, 2026

57 people who take Vimovo and Ambien together, and have interactions are studied.

What are the common drug interactions of Vimovo and Ambien, by gender? *:

female:

Chronic kidney disease
Renal failure (kidney dysfunction)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Hypertension (high blood pressure)
Arthralgia (joint pain)
Fall
Blood sodium decreased
Hallucination (an experience involving the perception of something not present)
Hypoaesthesia (reduced sense of touch or sensation)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Pruritus (severe itching of the skin)
Pyrexia (fever)
Abdominal pain
Arthralgia (joint pain)
Chills (felling of cold)
Death
Diarrhoea
Fatigue (feeling of tiredness)

What are the common drug interactions of Vimovo and Ambien, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Tuberculin test positive

30-39:

Gastrointestinal ulcer
Pancreatitis (inflammation of pancreas)
Papillary thyroid cancer
Post procedural hypothyroidism
Toxic nodular goitre (a thyroid gland that contains autonomously functioning thyroid nodules, with resulting excess thyroid hormone secretion)

40-49:

Arthralgia (joint pain)
Blood sodium decreased
Fall
Hallucination (an experience involving the perception of something not present)
Hypoaesthesia (reduced sense of touch or sensation)
Intervertebral disc protrusion (spinal disc protrusion)
Ligament rupture (tear in ligament)
Pain in extremity
Surgery
Chronic kidney disease

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Arthralgia (joint pain)
Asthenia (weakness)
Depression
Dry eye (lack of adequate tears)
Dry mouth
Dyspepsia (indigestion)
Fatigue (feeling of tiredness)
Headache (pain in head)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Developmental delay
Drug hypersensitivity
Fall
Femur fracture
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Haematochezia (passage of stools containing blood)
Hip fracture
Knee deformity (functional disability of knee)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 15 people, 26.32%
Indigestion: 12 people, 21.05%
Depression: 10 people, 17.54%
Pain: 9 people, 15.79%
High Blood Cholesterol: 9 people, 15.79%
Stress And Anxiety: 7 people, 12.28%
High Blood Pressure: 7 people, 12.28%
Diabetes: 7 people, 12.28%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 8.77%
Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 8.77%

* Approximation only. Some reports may have incomplete information.

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