Vimovo and Bystolic drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vimovo (esomeprazole magnesium; naproxen) and Bystolic (nebivolol hydrochloride). Common drug interactions include chronic kidney disease among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Vimovo and Bystolic. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Vimovo?

Vimovo has active ingredients of esomeprazole magnesium; naproxen. It is often used in osteoarthritis. eHealthMe is studying from 9,608 Vimovo users. Check the latest studies of Vimovo.

What is Bystolic?

Bystolic has active ingredients of nebivolol hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 20,662 Bystolic users. Check the latest studies of Bystolic.



On Jul, 16, 2026

26 people who take Vimovo and Bystolic together, and have interactions are studied.

Vimovo and Bystolic drug interactions.

What are the common drug interactions of Vimovo and Bystolic, by gender? *:

female:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Bacterial infection
  4. Headache (pain in head)
  5. Lower respiratory tract infection bacterial
  6. Renal disorder (kidney disease)
  7. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  8. Brain injury
  9. Carotid artery occlusion (artery blockage)
  10. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

male:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Headache (pain in head)
  4. Knee arthroplasty
  5. Palpitations (feelings or sensations that your heart is pounding or racing)
  6. Pruritus (severe itching of the skin)
  7. Pyrexia (fever)
  8. Renal failure (kidney dysfunction)
  9. Arthropathy
  10. Drug ineffective

What are the common drug interactions of Vimovo and Bystolic, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Pancreatitis (inflammation of pancreas)
  2. Papillary thyroid cancer
  3. Post procedural hypothyroidism
  4. Toxic nodular goitre (a thyroid gland that contains autonomously functioning thyroid nodules, with resulting excess thyroid hormone secretion)

40-49:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Renal failure (kidney dysfunction)
  4. Abdominal pain
  5. Arthralgia (joint pain)
  6. Chills (felling of cold)
  7. Diarrhoea
  8. Headache (pain in head)
  9. Migraine (headache)
  10. Palpitations (feelings or sensations that your heart is pounding or racing)

50-59:

  1. Back injury
  2. Disturbance in attention
  3. Headache (pain in head)
  4. Bacterial infection
  5. Chronic kidney disease
  6. Drug ineffective
  7. Lower respiratory tract infection bacterial
  8. Renal disorder (kidney disease)
  9. Renal failure (kidney dysfunction)
  10. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

60+:

  1. Chronic kidney disease
  2. Knee arthroplasty
  3. Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 11.54%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 11.54%
  3. Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 11.54%
  4. Depression: 3 people, 11.54%
  5. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 11.54%
  6. Thyroid Diseases: 2 people, 7.69%
  7. Stress And Anxiety: 2 people, 7.69%
  8. Rickets (softening of bones): 2 people, 7.69%
  9. Pain: 2 people, 7.69%
  10. Leukopenia (less number of white blood cells in blood): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Vimovo and Bystolic?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vimovo and Bystolic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vimovo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Bystolic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vimovo and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bystolic and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on esomeprazole magnesium; naproxen and nebivolol hydrochloride (the active ingredients of Vimovo and Bystolic, respectively), and Vimovo and Bystolic (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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