Vimovo and Miralax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vimovo (esomeprazole magnesium; naproxen) and Miralax (polyethylene glycol 3350). Common drug interactions include human chorionic gonadotropin increased among females and haemolysis among males.

The phase IV clinical study analyzes what interactions people have when they take Vimovo and Miralax. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Vimovo?

Vimovo has active ingredients of esomeprazole magnesium; naproxen. It is often used in osteoarthritis. eHealthMe is studying from 9,608 Vimovo users. Check the latest studies of Vimovo.

What is Miralax?

Miralax has active ingredients of polyethylene glycol 3350. It is often used in constipation. eHealthMe is studying from 81,754 Miralax users. Check the latest studies of Miralax.



On Aug, 12, 2026

36 people who take Vimovo and Miralax together, and have interactions are studied.

Vimovo and Miralax drug interactions.

What are the common drug interactions of Vimovo and Miralax, by gender? *:

female:

  1. Human chorionic gonadotropin increased
  2. Chronic kidney disease
  3. Renal failure (kidney dysfunction)
  4. Fibromyalgia (a long-term condition which causes pain all over the body)
  5. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  6. Anxiety
  7. Balance disorder
  8. Depression
  9. Dry mouth
  10. Fall

male:

  1. Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
  2. Oesophageal squamous cell carcinoma (cancer that begins in flat cells lining the oesophagus)
  3. Plasma cell myeloma (cancer that begins in plasma cells)
  4. Pulmonary embolism (blockage of the main artery of the lung)
  5. Renal failure acute (rapid kidney dysfunction)
  6. Syncope (loss of consciousness with an inability to maintain postural tone)
  7. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  8. Oesophageal ulcer (ulcer of oesophagus)
  9. Cardiac arrest
  10. Chronic kidney disease

What are the common drug interactions of Vimovo and Miralax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  2. Chronic kidney disease
  3. Renal failure (kidney dysfunction)
  4. Renal impairment (severely reduced kidney function)
  5. Hypertension (high blood pressure)

50-59:

  1. Human chorionic gonadotropin increased
  2. Accident at work
  3. Arthralgia (joint pain)
  4. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  5. Impaired work ability
  6. Limb injury
  7. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  8. Pain in jaw
  9. Trigeminal neuralgia (a painful condition of the nerve responsible for most facial sensation)

60+:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  4. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  5. Fatigue (feeling of tiredness)
  6. Plasma cell myeloma (cancer that begins in plasma cells)
  7. Pulmonary embolism (blockage of the main artery of the lung)
  8. Renal failure acute (rapid kidney dysfunction)
  9. Syncope (loss of consciousness with an inability to maintain postural tone)
  10. Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 12 people, 33.33%
  2. Insomnia (sleeplessness): 11 people, 30.56%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 16.67%
  4. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 13.89%
  5. Pain: 4 people, 11.11%
  6. Blood Pressure Abnormal: 3 people, 8.33%
  7. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 3 people, 8.33%
  8. Joint Pain: 3 people, 8.33%
  9. Itching: 3 people, 8.33%
  10. Renal Disorder (kidney disease): 3 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vimovo and Miralax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vimovo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Miralax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vimovo and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Miralax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on esomeprazole magnesium; naproxen and polyethylene glycol 3350 (the active ingredients of Vimovo and Miralax, respectively), and Vimovo and Miralax (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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