Vimovo and Motrin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vimovo (esomeprazole magnesium; naproxen) and Motrin (ibuprofen). Common drug interactions include arthritis among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Vimovo and Motrin. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Vimovo?

Vimovo has active ingredients of esomeprazole magnesium; naproxen. It is often used in osteoarthritis. eHealthMe is studying from 9,608 Vimovo users. Check the latest studies of Vimovo.

What is Motrin?

Motrin has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 38,332 Motrin users. Check the latest studies of Motrin.

On Jul, 12, 2026

16 people who take Vimovo and Motrin together, and have interactions are studied.

What are the common drug interactions of Vimovo and Motrin, by gender? *:

female:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood pressure increased
Bone density decreased
Bone disorder
Calcium deficiency (lack of calcium)
Crying
Depression
Dizziness
Drug intolerance (drug sensitivity)
Exostosis (formation of new bone on the surface of a bone)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Death
Failure to thrive (inadequate weight gain and physical growth in children)
Nephrogenic anaemia (anaemia due to kidney disease)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

What are the common drug interactions of Vimovo and Motrin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

50-59:

Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Dizziness
Renal failure (kidney dysfunction)
Throat tightness
Chronic kidney disease
Renal injury (kidney injury)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Dementia alzheimer's type (loss of mental ability with alzheimer's symptom)
Failure to thrive (inadequate weight gain and physical growth in children)
Nephrogenic anaemia (anaemia due to kidney disease)
Drug intolerance (drug sensitivity)
Peripheral swelling
Rectal haemorrhage (bleeding from anus)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 50.00%
High Blood Cholesterol: 7 people, 43.75%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 31.25%
Diabetes: 5 people, 31.25%
Nausea (feeling of having an urge to vomit): 4 people, 25.00%
Thyroid Diseases: 4 people, 25.00%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 3 people, 18.75%
Cardiac Disorder: 3 people, 18.75%
Insomnia (sleeplessness): 3 people, 18.75%
Depression: 3 people, 18.75%

* Approximation only. Some reports may have incomplete information.

Do you take Vimovo and Motrin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously