Vimovo and Sertraline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vimovo (esomeprazole magnesium; naproxen) and Sertraline (sertraline hydrochloride). Common drug interactions include retinal tear among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Vimovo and Sertraline. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Vimovo?

Vimovo has active ingredients of esomeprazole magnesium; naproxen. It is often used in osteoarthritis. eHealthMe is studying from 9,608 Vimovo users. Check the latest studies of Vimovo.

What is Sertraline?

Sertraline has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 153,304 Sertraline users. Check the latest studies of Sertraline.

On Jul, 07, 2026

58 people who take Vimovo and Sertraline together, and have interactions are studied.

Vimovo and Sertraline drug interactions.

What are the common drug interactions of Vimovo and Sertraline, by gender? *:

female:

Retinal tear
Sleep disorder
Spinal fracture (fracture in one of vertebrae)
Swelling face
Chronic kidney disease
Renal failure (kidney dysfunction)
Erythema (redness of the skin)
Pain in extremity
Pruritus (severe itching of the skin)
Arthralgia (joint pain)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Cardiac arrest
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Diabetes mellitus inadequate control
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Infarction (obstruction of the blood supply to an organ or region of tissue)
Infection
Neck pain

What are the common drug interactions of Vimovo and Sertraline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Ankylosing spondylitis (type of arthritis affecting the spine)
Arthralgia (joint pain)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Bone disorder
Drug ineffective
Dry skin
Emotional disorder
Erythema (redness of the skin)
Hypokinesia (decreased bodily movement)
Injection site discolouration

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Nephrogenic anaemia (anaemia due to kidney disease)
Pruritus (severe itching of the skin)
Arthralgia (joint pain)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Drug ineffective
Dry skin
Erythema (redness of the skin)
Injection site discolouration

50-59:

Chronic kidney disease
Bacterial infection
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Lower respiratory tract infection bacterial
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Arthralgia (joint pain)
Asthenia (weakness)
Cardiac arrest

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Insomnia (sleeplessness)
Sepsis (a severe blood infection that can lead to organ failure and death)
Intestinal perforation (complete penetration of the wall of the intestine)
Abdominal pain upper
Abnormal faeces (abnormal stool)
Anal fissure
Anal haemorrhage
Asthenia (weakness)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 23 people, 39.66%
Pain: 17 people, 29.31%
High Blood Pressure: 10 people, 17.24%
Diabetes: 8 people, 13.79%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 6 people, 10.34%
High Blood Cholesterol: 6 people, 10.34%
Gout (uric acid crystals building up in the body): 5 people, 8.62%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 8.62%
Cardiac Disorder: 5 people, 8.62%
Anaemia (lack of blood): 4 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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