Vimovo and Tobrex drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Vimovo (esomeprazole magnesium; naproxen) and Tobrex (tobramycin). Common drug interactions include blister among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Vimovo and Tobrex. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Vimovo?
Vimovo has active ingredients of esomeprazole magnesium; naproxen. It is often used in osteoarthritis. eHealthMe is studying from 9,608 Vimovo users. Check the latest studies of Vimovo.
What is Tobrex?
Tobrex has active ingredients of tobramycin. eHealthMe is studying from 762 Tobrex users. Check the latest studies of Tobrex.
11 people who take Vimovo and Tobrex together, and have interactions are studied.

What are the common drug interactions of Vimovo and Tobrex, by gender? *:
female:
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Drug hypersensitivity
- Rash
- Vision blurred
male:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Dyspepsia (indigestion)
- Fistula (an abnormal connection or passageway between two)
- Proteinuria (presence of protein in the urine)
- Renal atrophy (wasting of kidney)
- Disturbance in attention
- Infection
What are the common drug interactions of Vimovo and Tobrex, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Drug hypersensitivity
- Rash
- Vision blurred
60+:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Dyspepsia (indigestion)
- Fistula (an abnormal connection or passageway between two)
- Proteinuria (presence of protein in the urine)
- Renal atrophy (wasting of kidney)
- Disturbance in attention
- Infection
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 63.64%
- Pain: 3 people, 27.27%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 18.18%
* Approximation only. Some reports may have incomplete information.
Do you take Vimovo and Tobrex?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Vimovo and Tobrex:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Vimovo:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tobrex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vimovo and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tobrex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on esomeprazole magnesium; naproxen and tobramycin (the active ingredients of Vimovo and Tobrex, respectively), and Vimovo and Tobrex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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