Vimpat and Cotrim drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vimpat (lacosamide) and Cotrim (sulfamethoxazole; trimethoprim). Common drug interactions include atrial fibrillation among females.

The phase IV clinical study analyzes what interactions people have when they take Vimpat and Cotrim. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,831 Vimpat users. Check the latest studies of Vimpat.

What is Cotrim?

Cotrim has active ingredients of sulfamethoxazole; trimethoprim. eHealthMe is studying from 8,890 Cotrim users. Check the latest studies of Cotrim.

On Jul, 27, 2026

11 people who take Vimpat and Cotrim together, and have interactions are studied.

What are the common drug interactions of Vimpat and Cotrim, by gender? *:

female:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Arrhythmia (irregular heartbeat)
May-thurner syndrome (a rarely diagnosed condition in which patients develop iliofemoral deep venous thrombosis (dvt) due to an anatomical variant)
Moyamoya disease (a disease in which certain arteries in the brain are constricted. blood flow is blocked by the constriction)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Post procedural haemorrhage (post procedural bleeding)
Pyrexia (fever)
Renal failure (kidney dysfunction)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Urinary tract infection

male:

n/a

What are the common drug interactions of Vimpat and Cotrim, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

20-29:

n/a

30-39:

n/a

40-49:

Lymphopenia (an abnormally low level of lymphocytes in the blood)
May-thurner syndrome (a rarely diagnosed condition in which patients develop iliofemoral deep venous thrombosis (dvt) due to an anatomical variant)
Moyamoya disease (a disease in which certain arteries in the brain are constricted. blood flow is blocked by the constriction)
Post procedural haemorrhage (post procedural bleeding)
Pyrexia (fever)
Renal failure (kidney dysfunction)
Urinary tract infection
Normochromic normocytic anaemia (forms of anaemia in which the average size and haemoglobin content of the red blood cells are within normal limits)
C-reactive protein increased
Deep vein thrombosis postoperative (blood clot in a major vein that usually develops in the legs and/or pelvis after operation)

50-59:

Acquired epileptic aphasia (loss of language abilities in epilepsy)
Generalised non-convulsive epilepsy (epilepsy without convulsions)

60+:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Arrhythmia (irregular heartbeat)
Cardiac failure
Drug ineffective
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

What are the existing conditions these people have? *

Rickets (softening of bones): 4 people, 36.36%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 36.36%
Vitamin B Complex Deficiency: 2 people, 18.18%
Scurvy (a disease caused by deficiency of vitamin c, characterized by spongy and bleeding gums, bleeding under the skin, and extreme weakness): 2 people, 18.18%
Partial Seizures (seizures which affect only a part of the brain at onset): 2 people, 18.18%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 2 people, 18.18%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 18.18%
High Blood Pressure: 2 people, 18.18%
High Blood Cholesterol: 2 people, 18.18%
Constipation: 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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