Vimpat and Enhertu drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Vimpat (lacosamide) and Enhertu (fam-trastuzumab deruxtecan-nxki). Common drug interactions include interstitial lung disease among females.
The phase IV clinical study analyzes what interactions people have when they take Vimpat and Enhertu. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Vimpat?
Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,832 Vimpat users. Check the latest studies of Vimpat.
What is Enhertu?
Enhertu has active ingredients of fam-trastuzumab deruxtecan-nxki. eHealthMe is studying from 5,113 Enhertu users. Check the latest studies of Enhertu.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
13 people who take Vimpat and Enhertu together, and have interactions are studied.

What are the common drug interactions of Vimpat and Enhertu, by gender? *:
female:
- Interstitial lung disease
- White blood cell count decreased
- Hemianopia (blindness or reduction in vision in one half of the visual field due to damage of the optic pathways in the brain)
- Nausea (feeling of having an urge to vomit)
- Skin fissures (a crack in the skin)
- Thrombocytopenia (decrease of platelets in blood)
- Diarrhoea
- Neutropenia (an abnormally low number of neutrophils)
- Prerenal failure
- Vomiting
male:
n/a
What are the common drug interactions of Vimpat and Enhertu, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Interstitial lung disease
60+:
- Diarrhoea
- Neutropenia (an abnormally low number of neutrophils)
- Prerenal failure
- Vomiting
What are the existing conditions these people have? *
- Breast Cancer: 10 people, 76.92%
- Gastric Ulcer (stomach ulcer): 8 people, 61.54%
- Drug Hypersensitivity: 8 people, 61.54%
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 8 people, 61.54%
- Hypersensitivity: 2 people, 15.38%
- Sleep Disorder: 1 person, 7.69%
- Pain: 1 person, 7.69%
- Nausea (feeling of having an urge to vomit): 1 person, 7.69%
- High Blood Pressure: 1 person, 7.69%
- Headache (pain in head): 1 person, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Vimpat and Enhertu?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Vimpat and Enhertu:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Vimpat:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Enhertu:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vimpat and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Enhertu and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on lacosamide and fam-trastuzumab deruxtecan-nxki (the active ingredients of Vimpat and Enhertu, respectively), and Vimpat and Enhertu (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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