Vimpat and Humira drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vimpat (lacosamide) and Humira (adalimumab). Common drug interactions include tooth infection among females and foetal exposure during pregnancy among males.

The phase IV clinical study analyzes what interactions people have when they take Vimpat and Humira. It is created by eHealthMe based on reports of 98 people who take the same drugs from the FDA, and is updated regularly.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,831 Vimpat users. Check the latest studies of Vimpat.

What is Humira?

Humira has active ingredients of adalimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 761,396 Humira users. Check the latest studies of Humira.



On Jul, 09, 2026

98 people who take Vimpat and Humira together, and have interactions are studied.

Vimpat and Humira drug interactions.

What are the common drug interactions of Vimpat and Humira, by gender? *:

female:

  1. Tooth infection
  2. Injection site pain
  3. Sinusitis (inflammation of sinus)
  4. Erythema (redness of the skin)
  5. Fatigue (feeling of tiredness)
  6. Headache (pain in head)
  7. Pain
  8. Seasonal allergy (allergic condition due to certain season)
  9. Vision blurred
  10. Dizziness

male:

  1. Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
  2. Craniocerebral injury (injury to cranium and brain)
  3. Diplopia (double vision)
  4. Dry eye (lack of adequate tears)
  5. Erythema (redness of the skin)
  6. Eye pain
  7. Fall
  8. Foreign body sensation in eyes (feeling of something in eye)
  9. Ill-defined disorder
  10. Lung neoplasm malignant (cancer tumour of lung)

What are the common drug interactions of Vimpat and Humira, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Blood creatine phosphokinase increased
  2. Drug ineffective
  3. Escherichia infection (bacterial infection by escherichia coli)
  4. Genital swelling
  5. Urinary tract infection
  6. Partial seizures (seizures which affect only a part of the brain at onset)

20-29:

  1. Burning sensation
  2. Drug ineffective
  3. Limb injury
  4. Thermal burn (burn by heat)
  5. Wound necrosis (damaged cell of wound)
  6. Balance disorder
  7. Bedridden
  8. Diarrhoea
  9. Enterococcal infection
  10. Exaggerated startle response

30-39:

  1. Weight decreased
  2. Dysarthria (speech disorder)
  3. Influenza
  4. Optic neuritis (optic nerve inflammation)
  5. Psychotic disorder
  6. Pyrexia (fever)
  7. Sinusitis (inflammation of sinus)
  8. Tremor (trembling or shaking movements in one or more parts of your body)
  9. Ulcer haemorrhage (bleeding ulcer)
  10. Vision blurred

40-49:

  1. Pulmonary embolism (blockage of the main artery of the lung)
  2. Drug ineffective
  3. Fatigue (feeling of tiredness)
  4. Blindness
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Dyspnoea (difficult or laboured respiration)
  7. Joint stiffness
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Myalgia (muscle pain)
  10. Pain of skin

50-59:

  1. Tooth infection
  2. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  3. Dysarthria (speech disorder)
  4. Eosinophilia (eosinophil count in the peripheral blood exceeds)
  5. Erythema (redness of the skin)
  6. Headache (pain in head)
  7. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  8. Toxic skin eruption (skin breakdown due to toxic substance)
  9. Cerebral haemorrhage (bleeding within the brain)
  10. Concussion (short loss of normal brain function in response to a head injury)

60+:

  1. Craniocerebral injury (injury to cranium and brain)
  2. Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
  3. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  4. Diplopia (double vision)
  5. Dry eye (lack of adequate tears)
  6. Dyspnoea (difficult or laboured respiration)
  7. Eye pain
  8. Foreign body sensation in eyes (feeling of something in eye)
  9. Gait disturbance
  10. Ill-defined disorder

What are the existing conditions these people have? *

  1. Psoriasis (immune-mediated disease that affects the skin): 20 people, 20.41%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 20 people, 20.41%
  3. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 18 people, 18.37%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 12.24%
  5. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 10 people, 10.20%
  6. Pain: 10 people, 10.20%
  7. High Blood Pressure: 10 people, 10.20%
  8. Stress And Anxiety: 7 people, 7.14%
  9. Migraine (headache): 7 people, 7.14%
  10. Lambert-Eaton Syndrome (this means your immune system mistakenly targets healthy cells and tissues in the body): 7 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vimpat and Humira:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vimpat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Humira:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vimpat and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Humira and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on lacosamide and adalimumab (the active ingredients of Vimpat and Humira, respectively), and Vimpat and Humira (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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