Vimpat and Hydrocodone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vimpat (lacosamide) and Hydrocodone (hydrocodone bitartrate; ibuprofen). Common drug interactions include anxiety among females and abdominal distension among males.

The phase IV clinical study analyzes what interactions people have when they take Vimpat and Hydrocodone. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,831 Vimpat users. Check the latest studies of Vimpat.

What is Hydrocodone?

Hydrocodone has active ingredients of hydrocodone bitartrate; ibuprofen. eHealthMe is studying from 13,115 Hydrocodone users. Check the latest studies of Hydrocodone.

On Jul, 14, 2026

17 people who take Vimpat and Hydrocodone together, and have interactions are studied.

Vimpat and Hydrocodone drug interactions.

What are the common drug interactions of Vimpat and Hydrocodone, by gender? *:

female:

Anxiety
Chronic kidney disease
Depression
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Nephrogenic anaemia (anaemia due to kidney disease)
Polyp
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Fall

male:

Abdominal distension
Abdominal pain
Ear pain
Erythema (redness of the skin)
Eye irritation
Facial pain
Fatigue (feeling of tiredness)
Increased appetite
Induration (thickening of tissue)
Infusion site pruritus (severe itching at infusion site)

What are the common drug interactions of Vimpat and Hydrocodone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Dry eye (lack of adequate tears)
Chest discomfort
Cough
Dyspnoea (difficult or laboured respiration)
Induration (thickening of tissue)
Infusion site pruritus (severe itching at infusion site)
Infusion site urticaria (rash of round, red welts on the skin at infusion site)
Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
Urticaria (rash of round, red welts on the skin that itch intensely)
Wheezing (a high-pitched whistling sound made while you breath)

30-39:

Pneumonia

40-49:

Generalised anxiety disorder (excessive, uncontrollable, unexplained and often irrational worry)
Abdominal pain upper
Confusional state
Ear pain
Erythema (redness of the skin)
Eye irritation
Facial pain
Loss of consciousness
Memory impairment
Pharyngeal haemorrhage (pharyngeal bleeding)

50-59:

Ligament sprain (ligament stretched)
Neuralgia (pain in one or more nerves)
Rectal haemorrhage (bleeding from anus)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Gait disturbance
Nerve compression
Pulmonary mass
Vertigo positional
Headache (pain in head)
Infection

60+:

Anxiety
Chronic kidney disease
Depression
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Nephrogenic anaemia (anaemia due to kidney disease)
Polyp
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

What are the existing conditions these people have? *

Pain: 3 people, 17.65%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 17.65%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 17.65%
Immunodeficiency Common Variable: 3 people, 17.65%
Nausea (feeling of having an urge to vomit): 2 people, 11.76%
Essential Tremor: 2 people, 11.76%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 11.76%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 11.76%
Depression: 2 people, 11.76%
Insomnia (sleeplessness): 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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