Vimpat and Hydrodiuril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vimpat (lacosamide) and Hydrodiuril (hydrochlorothiazide). Common drug interactions include death among females and overdose among males.

The phase IV clinical study analyzes what interactions people have when they take Vimpat and Hydrodiuril. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,831 Vimpat users. Check the latest studies of Vimpat.

What is Hydrodiuril?

Hydrodiuril has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 4,211 Hydrodiuril users. Check the latest studies of Hydrodiuril.



On Jul, 10, 2026

12 people who take Vimpat and Hydrodiuril together, and have interactions are studied.

Vimpat and Hydrodiuril drug interactions.

What are the common drug interactions of Vimpat and Hydrodiuril, by gender? *:

female:

  1. Death
  2. Headache (pain in head)
  3. Overdose
  4. Confusional state
  5. Dizziness
  6. Electrocardiogram pr prolongation
  7. Electrocardiogram qt prolonged
  8. Partial seizures (seizures which affect only a part of the brain at onset)
  9. Contusion (a type of hematoma of tissue in which capillaries)
  10. Fall

male:

  1. Overdose
  2. Dyspnoea (difficult or laboured respiration)
  3. Hospitalisation
  4. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  5. Oedema peripheral (superficial swelling)
  6. Weight increased

What are the common drug interactions of Vimpat and Hydrodiuril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Headache (pain in head)
  2. Overdose
  3. Partial seizures (seizures which affect only a part of the brain at onset)

60+:

  1. Contusion (a type of hematoma of tissue in which capillaries)
  2. Death
  3. Fall
  4. Partial seizures (seizures which affect only a part of the brain at onset)
  5. Subdural haematoma (blood collects between the skull and the surface of the brain)
  6. Dyspnoea (difficult or laboured respiration)
  7. Hospitalisation
  8. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  9. Oedema peripheral (superficial swelling)
  10. Weight increased

What are the existing conditions these people have? *

  1. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 41.67%
  2. Partial Seizures (seizures which affect only a part of the brain at onset): 3 people, 25.00%
  3. Pain: 2 people, 16.67%
  4. High Blood Cholesterol: 2 people, 16.67%
  5. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 2 people, 16.67%
  6. Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 16.67%
  7. Stress And Anxiety: 1 person, 8.33%
  8. Nausea (feeling of having an urge to vomit): 1 person, 8.33%
  9. Headache (pain in head): 1 person, 8.33%
  10. Fever: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Vimpat and Hydrodiuril?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vimpat and Hydrodiuril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vimpat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hydrodiuril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vimpat and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydrodiuril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on lacosamide and hydrochlorothiazide (the active ingredients of Vimpat and Hydrodiuril, respectively), and Vimpat and Hydrodiuril (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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