Vimpat and Percocet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vimpat (lacosamide) and Percocet (acetaminophen; oxycodone hydrochloride). Common drug interactions include paraesthesia among females and urinary tract infection among males.

The phase IV clinical study analyzes what interactions people have when they take Vimpat and Percocet. It is created by eHealthMe based on reports of 90 people who take the same drugs from the FDA, and is updated regularly.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,832 Vimpat users. Check the latest studies of Vimpat.

What is Percocet?

Percocet has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 119,838 Percocet users. Check the latest studies of Percocet.

On Aug, 10, 2026

90 people who take Vimpat and Percocet together, and have interactions are studied.

What are the common drug interactions of Vimpat and Percocet, by gender? *:

female:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pulmonary embolism (blockage of the main artery of the lung)
Speech disorder
Vomiting
Back disorder
Bedridden
Cholecystitis (infection of gallbladder)
Delirium (wild excitement)
Gait disturbance
Gastrointestinal necrosis (destruction of gastrointestinal organ)

male:

Urinary tract infection
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Nausea (feeling of having an urge to vomit)
Abdominal pain
Faecal incontinence (a lack of control over passing stool)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Myelitis transverse (a neurological condition consisting of an inflammatory process of the spinal cord)
Thrombocytopenia (decrease of platelets in blood)
Pain in extremity
Anxiety

What are the common drug interactions of Vimpat and Percocet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Balance disorder
Fall
Lower limb fracture

30-39:

Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Anaemia (lack of blood)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Enterobacter infection (infection caused by bacteria of the family enterobacteriaceae)
Pneumonia klebsiella (pneumonia caused by bacteria klebsiella)
Hepatic enzyme increased
Hypernatraemia (an abnormally high plasma concentration of sodium ions)
Iron deficiency
Alanine aminotransferase increased

40-49:

Stress
Urinary tract infection bacterial
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Back disorder
Bedridden
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Migraine (headache)
Nasopharyngitis (inflammation of the nasopharynx)
Ankle fracture
Arthralgia (joint pain)

50-59:

Urinary tract infection
Death
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Fatigue (feeling of tiredness)
Fall
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Oedema (fluid collection in tissue)
Oedema peripheral (superficial swelling)
Tremor (trembling or shaking movements in one or more parts of your body)
Diarrhoea

60+:

Cholecystitis (infection of gallbladder)
Dehydration (dryness resulting from the removal of water)
Alopecia (absence of hair from areas of the body)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Arthropathy
Balance disorder
Blood pressure increased
Bone disorder
Cardiac failure congestive
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

What are the existing conditions these people have? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 29 people, 32.22%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 26 people, 28.89%
Nausea (feeling of having an urge to vomit): 23 people, 25.56%
Stress And Anxiety: 18 people, 20.00%
Insomnia (sleeplessness): 18 people, 20.00%
Urinary Tract Infection: 15 people, 16.67%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 14 people, 15.56%
Sepsis (a severe blood infection that can lead to organ failure and death): 14 people, 15.56%
Depression: 13 people, 14.44%
Diarrhea: 13 people, 14.44%

* Approximation only. Some reports may have incomplete information.

Do you take Vimpat and Percocet?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously