Viracept and Peginterferon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Viracept (nelfinavir mesylate) and Peginterferon (peginterferon alfa-2a; ribavirin). Common drug interactions include haemorrhagic diathesis among females and haemorrhagic diathesis among males.

The phase IV clinical study analyzes what interactions people have when they take Viracept and Peginterferon. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Viracept?

Viracept has active ingredients of nelfinavir mesylate. It is often used in hiv infection. eHealthMe is studying from 6,399 Viracept users. Check the latest studies of Viracept.

What is Peginterferon?

Peginterferon has active ingredients of peginterferon alfa-2a; ribavirin. It is often used in hepatitis c. eHealthMe is studying from 13,778 Peginterferon users. Check the latest studies of Peginterferon.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 17, 2026

19 people who take Viracept and Peginterferon together, and have interactions are studied.

Viracept and Peginterferon drug interactions.

What are the common drug interactions of Viracept and Peginterferon, by gender? *:

female:

  1. Haemorrhagic diathesis (bleeding tendency)
  2. Hyperuricaemia (level of uric acid in the blood that is abnormally high)
  3. Liver disorder (liver diseases)
  4. Beta 2 microglobulin urine increased
  5. Choking (mechanical obstruction of the flow of air from the environment into the lungs)
  6. Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
  7. Acute hepatic failure
  8. Cytolytic hepatitis (dissolution or destruction of a liver cell)
  9. Drug exposure during pregnancy
  10. Drug toxicity

male:

  1. Haemorrhagic diathesis (bleeding tendency)
  2. Liver disorder (liver diseases)
  3. Post thrombotic syndrome (long-term effects that can occur after venous thrombosis)
  4. Staphylococcal infection (an infection with staphylococcus bacteria)
  5. Subdural haematoma (blood collects between the skull and the surface of the brain)
  6. Sudden death
  7. Tuberculin test positive
  8. Ulcer
  9. Beta 2 microglobulin urine increased
  10. Hyperuricaemia (level of uric acid in the blood that is abnormally high)

What are the common drug interactions of Viracept and Peginterferon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Haemorrhagic diathesis (bleeding tendency)
  2. Liver disorder (liver diseases)
  3. Hyperuricaemia (level of uric acid in the blood that is abnormally high)
  4. Beta 2 microglobulin urine increased
  5. Choking (mechanical obstruction of the flow of air from the environment into the lungs)
  6. Osteoporosis (bones weak and more likely to break)
  7. Haematoma (collection of blood outside the blood vessels)
  8. Haemoglobin decreased
  9. Lymphadenopathy (disease or enlargement of lymph nodes)
  10. Pneumocystis jiroveci pneumonia (fungal infection of the lungs)

40-49:

  1. Beta 2 microglobulin urine increased
  2. Mobility decreased (ability to move is reduced)
  3. Muscle disorder (muscle disease)
  4. Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles)
  5. Subdural haematoma (blood collects between the skull and the surface of the brain)
  6. Sudden death
  7. Haemorrhagic diathesis (bleeding tendency)
  8. Hyperuricaemia (level of uric acid in the blood that is abnormally high)
  9. Liver disorder (liver diseases)
  10. Osteoporosis (bones weak and more likely to break)

50-59:

  1. Myositis (inflammation of the muscles)

60+:

n/a

What are the existing conditions these people have? *

  1. Liver Disorder (liver diseases): 13 people, 68.42%
  2. Hepatitis (inflammation of the liver): 13 people, 68.42%
  3. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 10 people, 52.63%
  4. High Blood Pressure: 8 people, 42.11%
  5. Osteoporosis (bones weak and more likely to break): 5 people, 26.32%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 15.79%
  7. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.26%
  8. Hiv Test Positive: 1 person, 5.26%
  9. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Viracept and Peginterferon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Viracept:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Peginterferon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Viracept and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Peginterferon and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on nelfinavir mesylate and peginterferon alfa-2a; ribavirin (the active ingredients of Viracept and Peginterferon, respectively), and Viracept and Peginterferon (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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