Viread and Zemplar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Viread (tenofovir disoproxil fumarate) and Zemplar (paricalcitol). Common drug interactions include anhedonia among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Viread and Zemplar. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Viread?

Viread has active ingredients of tenofovir disoproxil fumarate. It is often used in hepatitis b. eHealthMe is studying from 51,542 Viread users. Check the latest studies of Viread.

What is Zemplar?

Zemplar has active ingredients of paricalcitol. It is often used in kidney disease. eHealthMe is studying from 15,494 Zemplar users. Check the latest studies of Zemplar.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

13 people who take Viread and Zemplar together, and have interactions are studied.

What are the common drug interactions of Viread and Zemplar, by gender? *:

female:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Depression
Emotional distress
Pain
Pituitary-dependent cushing's syndrome (pituitary dependent hypercortisolism)

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Mobility decreased (ability to move is reduced)
Social problem
Depression
Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium)
Asthenia (weakness)
Bone density decreased
Tooth loss
Panic attack

What are the common drug interactions of Viread and Zemplar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Decreased activity
Emotional distress
Fatigue (feeling of tiredness)
Loss of employment
Mobility decreased (ability to move is reduced)
Pain
Quality of life decreased
Social problem

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Emotional distress
Pain
Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium)
Renal failure (kidney dysfunction)

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Depression
Emotional distress
Pain
Renal failure (kidney dysfunction)

60+:

Dehydration (dryness resulting from the removal of water)
Hyperkalaemia (damage to or disease of the kidney)
Renal failure acute (rapid kidney dysfunction)

What are the existing conditions these people have? *

Hiv Infection: 12 people, 92.31%
Chronic Kidney Disease: 3 people, 23.08%
Depression: 3 people, 23.08%
Erection Problems: 3 people, 23.08%
High Blood Pressure: 3 people, 23.08%
Stress And Anxiety: 3 people, 23.08%
Hypersensitivity: 2 people, 15.38%
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood): 2 people, 15.38%
Cough: 2 people, 15.38%
Emotional Distress: 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

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