Vistaril and Arthrotec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vistaril (hydroxyzine hydrochloride) and Arthrotec (diclofenac sodium; misoprostol). Common drug interactions include aggression among females and depression among males.

The phase IV clinical study analyzes what interactions people have when they take Vistaril and Arthrotec. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Vistaril?

Vistaril has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,565 Vistaril users. Check the latest studies of Vistaril.

What is Arthrotec?

Arthrotec has active ingredients of diclofenac sodium; misoprostol. It is often used in arthritis. eHealthMe is studying from 11,986 Arthrotec users. Check the latest studies of Arthrotec.



On Jul, 15, 2026

22 people who take Vistaril and Arthrotec together, and have interactions are studied.

Vistaril and Arthrotec drug interactions.

What are the common drug interactions of Vistaril and Arthrotec, by gender? *:

female:

  1. Aggression
  2. Anaemia (lack of blood)
  3. Anaphylactic reaction (serious allergic reaction)
  4. Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
  5. Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
  6. Back injury
  7. Back pain
  8. Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
  9. Bladder prolapse (bulging of one or more of the pelvic organs into the vagina)
  10. Brain stem stroke (rapid loss of brain function due to disturbance in the blood supply to the brain)

male:

  1. Depression
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Hallucination (an experience involving the perception of something not present)
  4. Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)
  5. Peptic ulcer
  6. Pneumonia
  7. Somnolence (a state of near-sleep, a strong desire for sleep)
  8. Unresponsive to stimuli
  9. Urinary tract infection
  10. Cough

What are the common drug interactions of Vistaril and Arthrotec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Type 2 diabetes mellitus
  2. Affective disorder (mental disorder)
  3. Aggression
  4. Alcoholic pancreatitis
  5. Arthralgia (joint pain)
  6. Back injury
  7. Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
  8. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  9. Constipation
  10. Contusion (a type of hematoma of tissue in which capillaries)

40-49:

  1. Asthenia (weakness)
  2. Back injury
  3. Back pain
  4. Brain stem stroke (rapid loss of brain function due to disturbance in the blood supply to the brain)
  5. Cellulitis (infection under the skin)
  6. Cervical myelopathy (clinical syndrome characterized by clumsiness in hands; gait imbalance; caused by compression of the spinal cord)
  7. Chest pain
  8. Chills (felling of cold)
  9. Constipation
  10. Contusion (a type of hematoma of tissue in which capillaries)

50-59:

  1. Completed suicide (act of taking one's own life)
  2. Contusion (a type of hematoma of tissue in which capillaries)
  3. Fall
  4. Herpes zoster
  5. Influenza like illness
  6. Urinary tract infection
  7. Anaphylactic reaction (serious allergic reaction)
  8. Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
  9. Arthralgia (joint pain)
  10. Breast tenderness

60+:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Hallucination (an experience involving the perception of something not present)
  4. Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)
  5. Peptic ulcer
  6. Pneumonia
  7. Somnolence (a state of near-sleep, a strong desire for sleep)
  8. Unresponsive to stimuli
  9. Urinary tract infection
  10. Cough

What are the existing conditions these people have? *

  1. Depression: 5 people, 22.73%
  2. Insomnia (sleeplessness): 4 people, 18.18%
  3. Cardiac Failure Chronic: 4 people, 18.18%
  4. Pain: 3 people, 13.64%
  5. Bipolar Disorder (mood disorder): 3 people, 13.64%
  6. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 9.09%
  7. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 9.09%
  8. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 2 people, 9.09%
  9. Diabetes: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vistaril and Arthrotec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vistaril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Arthrotec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vistaril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Arthrotec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on hydroxyzine hydrochloride and diclofenac sodium; misoprostol (the active ingredients of Vistaril and Arthrotec, respectively), and Vistaril and Arthrotec (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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