Vistaril and Avinza drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vistaril (hydroxyzine hydrochloride) and Avinza (morphine sulfate). Common drug interactions include myalgia among females and hyperhidrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Vistaril and Avinza. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Vistaril?

Vistaril has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,565 Vistaril users. Check the latest studies of Vistaril.

What is Avinza?

Avinza has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 1,728 Avinza users. Check the latest studies of Avinza.



On Aug, 03, 2026

12 people who take Vistaril and Avinza together, and have interactions are studied.

Vistaril and Avinza drug interactions.

What are the common drug interactions of Vistaril and Avinza, by gender? *:

female:

  1. Myalgia (muscle pain)
  2. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  3. Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
  4. Neck pain
  5. Neoplasm (tumour)
  6. Obesity (having too much body fat)
  7. Oedema peripheral (superficial swelling)
  8. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  9. Fall
  10. Malaise (a feeling of general discomfort or uneasiness)

male:

  1. Hyperhidrosis (abnormally increased sweating)
  2. Blood pressure increased
  3. Cold sweat
  4. Dyspnoea (difficult or laboured respiration)
  5. Increased upper airway secretion
  6. Death
  7. Depressed level of consciousness
  8. Dizziness
  9. Eating disorder
  10. Lethargy (tiredness)

What are the common drug interactions of Vistaril and Avinza, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Blood pressure increased
  2. Claustrophobia (fear of having no escape and being closed in small spaces)
  3. Drug ineffective
  4. Heart rate increased
  5. Hyperhidrosis (abnormally increased sweating)
  6. Psychomotor hyperactivity (feelings of extreme restlessness)
  7. Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
  8. Drug effect decreased
  9. Headache (pain in head)
  10. Pain in extremity

50-59:

  1. Overdose
  2. Pain in extremity
  3. Palpitations (feelings or sensations that your heart is pounding or racing)
  4. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  5. Dyspnoea (difficult or laboured respiration)
  6. Application site erythema (redness of the skin at application site)
  7. Application site pain
  8. Choking (mechanical obstruction of the flow of air from the environment into the lungs)
  9. Cold sweat
  10. Dizziness

60+:

  1. Abdominal discomfort
  2. Fall
  3. Arthralgia (joint pain)
  4. Bone pain
  5. Growing pains (child sometimes wake up crying in the middle of the night complaining of throbbing leg pain)
  6. Joint crepitation
  7. Nail discomfort
  8. Pain in extremity
  9. Diarrhoea
  10. Gastritis (inflammation of stomach)

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 5 people, 41.67%
  2. Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly): 2 people, 16.67%
  3. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 16.67%
  4. Intervertebral Disc Degeneration (spinal disc degeneration): 2 people, 16.67%
  5. Pain In Extremity: 1 person, 8.33%
  6. Nausea (feeling of having an urge to vomit): 1 person, 8.33%
  7. Gastric Cancer (stomach cancer): 1 person, 8.33%
  8. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 8.33%
  9. Chest Pain: 1 person, 8.33%
  10. Cardiac Failure Congestive: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vistaril and Avinza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vistaril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Avinza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vistaril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Avinza and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on hydroxyzine hydrochloride and morphine sulfate (the active ingredients of Vistaril and Avinza, respectively), and Vistaril and Avinza (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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