Vistaril and Fluconazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vistaril (hydroxyzine hydrochloride) and Fluconazole (fluconazole). Common drug interactions include hypoglycaemia among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Vistaril and Fluconazole. It is created by eHealthMe based on reports of 85 people who take the same drugs from the FDA, and is updated regularly.

What is Vistaril?

Vistaril has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,565 Vistaril users. Check the latest studies of Vistaril.

What is Fluconazole?

Fluconazole has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 70,481 Fluconazole users. Check the latest studies of Fluconazole.

On Jul, 17, 2026

85 people who take Vistaril and Fluconazole together, and have interactions are studied.

Vistaril and Fluconazole drug interactions.

What are the common drug interactions of Vistaril and Fluconazole, by gender? *:

female:

Hypoglycaemia (deficiency of glucose in the bloodstream)
International normalised ratio increased
Nausea (feeling of having an urge to vomit)
Vomiting
Weight decreased
Arthralgia (joint pain)
Depression
Emotional distress
Migraine (headache)
Abdominal pain

male:

Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Constipation
Dental caries
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Fall
Gait disturbance
Impaired work ability
Infection
Injury

What are the common drug interactions of Vistaril and Fluconazole, by age (0-1 to 60+)? *:

0-1:

C-reactive protein increased
Pericarditis (inflammation of the pericardium)
Pulmonary oedema (fluid accumulation in the lungs)
Pyrexia (fever)
White blood cell count increased
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Cardiac failure
Drug maladministration
Dyspnoea (difficult or laboured respiration)
Morose (sullen and ill-tempered)

2-9:

n/a

10-19:

Arrhythmia (irregular heartbeat)
Cardiac myxoma (tumour of the heart in adults)
Chest pain
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)

20-29:

Impaired work ability
Migraine (headache)
Myalgia (muscle pain)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Bedridden
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Decreased activity
Depression
Dizziness
Dyspnoea (difficult or laboured respiration)

30-39:

Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypoxia (low oxygen in tissues)
Nausea (feeling of having an urge to vomit)
Otitis media (inflammation of the middle ear)
Renal failure (kidney dysfunction)
Salivary hypersecretion (excess saliva secretion)
Terminal state (the transitional states between life and biological death)
Thrombocythaemia (an increased number of platelets in the circulating blood)

40-49:

Renal failure (kidney dysfunction)
Chronic kidney disease
Fatigue (feeling of tiredness)
Abdominal pain
Back pain
Arthralgia (joint pain)
Colonic polyp (extra part of colon tissue grow in intestine)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Cough
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

50-59:

Blood triglycerides increased
Chest pain
Dysmenorrhoea (painful menstruation)
Dyspnoea (difficult or laboured respiration)
Early satiety (feeling full before completing a normal sized meal)
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Metastases to lymph nodes (cancer spreads to lymph node)
Metastases to peritoneum (cancer spreads to peritoneum)
Nausea (feeling of having an urge to vomit)
Osteopenia (a condition where bone mineral density is lower than normal)

60+:

Pain
Vomiting
Constipation
Dental caries
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Fall
Fatigue (feeling of tiredness)
Gait disturbance
Infection
Injury

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 19 people, 22.35%
Pain: 18 people, 21.18%
Depression: 14 people, 16.47%
Constipation: 13 people, 15.29%
Nausea (feeling of having an urge to vomit): 10 people, 11.76%
Hypersensitivity: 10 people, 11.76%
High Blood Cholesterol: 10 people, 11.76%
High Blood Pressure: 9 people, 10.59%
Restless Leg Syndrome (a powerful urge to move your legs): 7 people, 8.24%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 8.24%

* Approximation only. Some reports may have incomplete information.

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