Vistaril and Glucotrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vistaril (hydroxyzine hydrochloride) and Glucotrol (glipizide). Common drug interactions include headache among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Vistaril and Glucotrol. It is created by eHealthMe based on reports of 98 people who take the same drugs from the FDA, and is updated regularly.

What is Vistaril?

Vistaril has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,565 Vistaril users. Check the latest studies of Vistaril.

What is Glucotrol?

Glucotrol has active ingredients of glipizide. It is often used in diabetes. eHealthMe is studying from 20,322 Glucotrol users. Check the latest studies of Glucotrol.



On Jul, 20, 2026

98 people who take Vistaril and Glucotrol together, and have interactions are studied.

Vistaril and Glucotrol drug interactions.

What are the common drug interactions of Vistaril and Glucotrol, by gender? *:

female:

  1. Headache (pain in head)
  2. Hyperglycaemia (high blood sugar)
  3. Renal failure (kidney dysfunction)
  4. Arthralgia (joint pain)
  5. Blood cholesterol increased
  6. Depression
  7. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  8. Dizziness
  9. Drug hypersensitivity
  10. Dyspnoea (difficult or laboured respiration)

male:

  1. Headache (pain in head)
  2. Nausea (feeling of having an urge to vomit)
  3. Abdominal pain
  4. Agitation (state of anxiety or nervous excitement)
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Vomiting
  7. Angina pectoris (chest pain due to ischemia of the heart muscle)
  8. Asthenia (weakness)
  9. Chest discomfort
  10. Diarrhoea

What are the common drug interactions of Vistaril and Glucotrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
  2. Bipolar disorder (mood disorder)
  3. Chest pain
  4. Confusional state
  5. Constipation
  6. Cough
  7. Dizziness
  8. Dyspnoea (difficult or laboured respiration)
  9. Dysthymic disorder (mild chronic depression disorder)
  10. Euphoric mood (excessively happy but may become angry or irritable)

30-39:

  1. Blood glucose increased
  2. Contusion (a type of hematoma of tissue in which capillaries)
  3. Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
  4. Excoriation (to tear or wear off the skin of)
  5. Headache (pain in head)
  6. Hypertension (high blood pressure)
  7. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  8. Tremor (trembling or shaking movements in one or more parts of your body)
  9. Agitation (state of anxiety or nervous excitement)
  10. Akathisia (a movement disorder characterized by a feeling of inner restlessness)

40-49:

  1. Tardive dyskinesia (a disorder that involves involuntary movements)
  2. Urinary tract infection
  3. Hyperglycaemia (high blood sugar)
  4. Abdominal pain
  5. Nausea (feeling of having an urge to vomit)
  6. Back pain
  7. Blood cholesterol increased
  8. Depression
  9. Hypoaesthesia (reduced sense of touch or sensation)
  10. Pain in extremity

50-59:

  1. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  2. Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
  3. Upper respiratory tract infection
  4. Urinary tract infection
  5. Vertigo
  6. Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
  7. Abdominal pain lower
  8. Angina pectoris (chest pain due to ischemia of the heart muscle)
  9. Arthralgia (joint pain)
  10. Blood triglycerides increased

60+:

  1. Nausea (feeling of having an urge to vomit)
  2. Pain
  3. Blood glucose increased
  4. Chest discomfort
  5. Constipation
  6. Deformity (disfigurement)
  7. Dehydration (dryness resulting from the removal of water)
  8. Depressed mood
  9. Diarrhoea
  10. Discomfort

What are the existing conditions these people have? *

  1. Depression: 24 people, 24.49%
  2. Pain: 12 people, 12.24%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 12.24%
  4. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 11 people, 11.22%
  5. Neoplasm Malignant (cancer tumour): 11 people, 11.22%
  6. Bipolar Disorder (mood disorder): 11 people, 11.22%
  7. Insomnia (sleeplessness): 10 people, 10.20%
  8. Type 2 Diabetes: 9 people, 9.18%
  9. Sleep Disorder: 9 people, 9.18%
  10. High Blood Pressure: 9 people, 9.18%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vistaril and Glucotrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vistaril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Glucotrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vistaril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Glucotrol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on hydroxyzine hydrochloride and glipizide (the active ingredients of Vistaril and Glucotrol, respectively), and Vistaril and Glucotrol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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